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Guidebook to Protein Toxins and Their Use in Cell Biology

von Rappuoli
New. Sprache: Englisch.
Buch (kartoniert)
Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of... weiterlesen
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Guidebook to Protein Toxins and Their Use in Cell Biology als Buch
Produktdetails
Titel: Guidebook to Protein Toxins and Their Use in Cell Biology
Autor/en: Rappuoli

ISBN: 0198599544
EAN: 9780198599548
New.
Sprache: Englisch.
Herausgegeben von Rino Rappuoli, Cesare Montecucco
OXFORD UNIV PR

April 1997 - kartoniert - 278 Seiten

Beschreibung

Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action. Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology, neuroscience, and toxicology.

Inhaltsverzeichnis

1. Membrane permeabilizing toxins; 2. Toxins affecting signal transduction; 3. Toxins affecting protein synthesis; 4. Cytoskeleton-affecting toxins; 5. Toxins affecting the immune and inflammatory response; 6. Toxins affecting membrane traffic; 7. Sodium channel-targeted toxins; 8. Potassium channel-targeted toxins; 9. Calcium channel-targeted toxins; 10. Acetylcholine receptor targeted toxins; 11. Ryanodine receptor toxins; 12. Presynaptic toxins; 13. Glutamate receptor-targeted toxins

Pressestimmen

The authors have concisely compiled structure, function, and toxicity data for 78 protein toxins in a unique, accessible format that allows cell biologists to learn how protein toxins have aided in the dissection of cellular processes. --Journal of Chemical Education
"Both our understanding of the actions of protein toxins and their uses as tools in cell biology have undergone an explosion in recent years. It almost seems that there is now a toxin to disrupt every aspect of cell metabolism. This volume is composed of short (1 to 3 page) summaries on the mechanism of action and uses of over 75 different protein toxins. It will be an invaluable reference for biological sciences and medical school libraries. Given the rapid pace of progress in this area, an additional attraction of this work is that updated information will be available on the World Wide Web."--The Quarterly Review of Biology

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