Warenkorb
€ 0,00 0 Buch dabei,
portofrei
Cell Migration in Inflammation and Immunity: Methods and Protocols als Buch
PORTO-
FREI

Cell Migration in Inflammation and Immunity: Methods and Protocols

Methods and Protocols. 'Methods in Molecular Biology'. Auflage 2003. Sprache: Englisch.
Buch (gebunden)
Ihr 12%-Rabatt auf alle Spielwaren, Hörbücher, Filme, Musik u.v.m
 
12% Rabatt sichern mit Gutscheincode: SONNE12
 
Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response t … weiterlesen
Buch

141,49*

inkl. MwSt.
Portofrei
Lieferbar innerhalb von ein bis zwei Wochen
Cell Migration in Inflammation and Immunity: Methods and Protocols als Buch

Produktdetails

Titel: Cell Migration in Inflammation and Immunity: Methods and Protocols

ISBN: 1588291022
EAN: 9781588291028
Methods and Protocols.
'Methods in Molecular Biology'.
Auflage 2003.
Sprache: Englisch.
Herausgegeben von Daniele D'Ambrosio, Francesco Sinigaglia
SPRINGER VERLAG GMBH

29. August 2003 - gebunden - 277 Seiten

Beschreibung

Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases. About 50 distinct chemokines produced by a variety cell types and tissues either c- stitutively or in response to inflammatory stimuli are involved in a plethora of biological processes. These small secreted proteins exert their exquisitely variegated functions upon binding to a family of seven-transmembrane spanning G-protein coupled receptors (GPCRs) composed of almost 20 distinct entities. The biological activities of chemokines range from the control of leukocyte trafficking in basal and inflammatory conditions to the regulation of hema- poiesis, angiogenesis, tissue architecture, and organogenesis. The basis for such diversified activities rests, on one hand, upon the ubiquitous nature of chemokine production and chemokine receptor expression. Virtually every cell type can produce chemokines and expresses a unique combination of chemokine receptors. On the other hand, chemokine receptors make use of a flexible and complex network of intracellular signaling machineries that can regulate a variety of cellular functions ranging from cell migration, growth, and differentiation to death. As knowledge of the size of chemokine and chemokine receptor families rapidly reaches completeness, much is still to be uncovered in terms of fu- tional architecture of the chemokine system. The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand-receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.

Inhaltsverzeichnis

Chemotaxis and Interaction with Vascular or Lymphatic Endothelium
Silvano Sozzani, Annunciata Vecchi, Paola Allavena, and Alberto Mantovani

Analysis of Integrin-Dependent Rapid Adhesion Under Laminar-Flow Conditions
Carlo Laudanna

Posttranslational Processing of Chemokines
Paul Proost, Frank Mahieu, Evemie Schutyser, and Jo Van Damme

Chemotactic Profiling of Lymphocyte Subpopulations
Lucia Colantonio, Andrea Iellem, and Daniele D'Ambrosio

Measurement of the Levels of Polymerized Actin (F-Actin) in Chemokine-Stimulated Lymphocytes and GFP-Coupled cDNA Transfected Lymphoid Cells by Flow Cytometry
Miguel Vicente-Manzanares, Mariano Vitón, and Francisco Sánchez-Madrid

Evaluation of Rho Family Small G-Protein Activity Induced by Integrin Ligation on Human Leukocytes
Angela Gismondi, Fabrizio Mainiero, and Angela Santoni

Reconstructing Leukocyte Migration in 3D Extracellular Matrix by Time-Lapse Videomicroscopy and Computer-Assisted Tracking
Peter Friedl and Eva-B. Bröcker

Analyzing Chemotaxis Using Dictyostelium discoideum as a Model System
Mark A. Landree and Peter N. Devreotes

Conditional Transgenic Models to Study Chemokine Biology
Sergio A. Lira, Borna Mehrad, Shu-Cheng Chen, Petronio Zalamea, David J. Kinsley, Maria T. Wiekowski, Elizabeth Coronel, Galya Vassileva, Denise Manfra, and Kristian K. Jensen

Intravital Microscopy as a Tool for Studying Recruitment and Chemotaxis
Denise C. Cara and Paul Kubes

Tracking Antigen-Specific Lymphocytes In Vivo
Claire L. Adams, Catherine M. Rush, Karen M. Smith, and Paul Garside

Analysis of Homing-Receptor Expression on Infiltrating Leukocytes in Disease States
Margherita Mariani and Paola Panina-Bordignon

Interaction of Viral Chemokine Inhibitors with Chemokines
Antonio Alcami

Discovery of Small-Molecule Antagonists ofChemokine Receptors: Screening Strategy and Assays
Maria Elena Fuentes

Visualization and Analysis of Adhesive Events in Brain Microvessels by Using Intravital Microscopy
Gabriela Constantin

Animal Models to Study Chemokine Receptor Function In Vivo: Mouse Models of Allergic Airway Inflammation
Clare M. Lloyd and Jose-Carlos Gutierrez-Ramos

Assessing the Role of Multiple Phosphoinositide 3-Kinases in Chemokine Signaling: Use of Dominant Negative Mutants Controlled by a Tetracycline-Regulated Gene Expression System
Adam P. Curnock, Yannis Sotsios, and Stephen G. Ward

In Vitro and In Vivo Models to Study Chemokine Regulation of Angiogenesis
Giovanni Bernardini, Domenico Ribatti, Gaia Spinetti, Lucia Morbidelli, Marina Ziche, Angela Santoni, Maurizio C. Capogrossi, and Monica Napolitano

Real Time In Vitro Assay for Studying Chemoattractant-Triggered Leukocyte Transendothelial Migration Under Physiological Flow Conditions
Guy Cinamon and Ronen Alon

Generation of Monoclonal Antibodies Against Chemokine Receptors
Leonor Kremer and Gabriel Márquez

Detection of High-Affinity a4-Integrin Upon Leukocyte Stimulation by Chemoattractants or Chemokines
Jason R. Chan and Myron I. Cybulsky

Index

Mehr aus dieser Reihe

zurück
Protocols for Micropropagation of Selected Economically-Important Horticultural Plants
- 9% **
Buch (gebunden)
Bisher € 165,49
Alzheimer's Disease and Frontotemporal Dementia
- 9% **
Buch (gebunden)
Bisher € 128,49
Clostridium Difficile: Methods and Protocols
Buch (gebunden)
Histology Protocols
Buch (gebunden)
Characterization of Nanoparticles Intended for Drug Delivery
Buch (gebunden)
vor
Servicehotline
089 - 70 80 99 47

Mo. - Fr. 8.00 - 20.00 Uhr
Sa. 10.00 - 20.00 Uhr
Filialhotline
089 - 30 75 75 75

Mo. - Sa. 9.00 - 20.00 Uhr
Bleiben Sie in Kontakt:
Sicher & bequem bezahlen:
akzeptierte Zahlungsarten: Überweisung, offene Rechnung,
Visa, Master Card, American Express, Paypal
Zustellung durch:
* Alle Preise verstehen sich inkl. der gesetzlichen MwSt. Informationen über den Versand und anfallende Versandkosten finden Sie hier.
** Deutschsprachige eBooks und Bücher dürfen aufgrund der in Deutschland geltenden Buchpreisbindung und/oder Vorgaben von Verlagen nicht rabattiert werden. Soweit von uns deutschsprachige eBooks und Bücher günstiger angezeigt werden, wurde bei diesen kürzlich von den Verlagen der Preis gesenkt oder die Buchpreisbindung wurde für diese Titel inzwischen aufgehoben. Angaben zu Preisnachlässen beziehen sich auf den dargestellten Vergleichspreis.