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Frontiers in Antimicrobial Resistance: A Tribute to Stuart B. Levy als Buch
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Frontiers in Antimicrobial Resistance: A Tribute to Stuart B. Levy

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Frontiers in Antimicrobial Resistance: a Tribute to Stuart B. Levy offers a unique examination of the state of antimicrobial and anticancer drug resistance. Written by acknowledged experts who have spent time in Dr. Levy's laboratory or who have othe … weiterlesen


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Frontiers in Antimicrobial Resistance: A Tribute to Stuart B. Levy als Buch


Titel: Frontiers in Antimicrobial Resistance: A Tribute to Stuart B. Levy

ISBN: 1555813291
EAN: 9781555813291
Sprache: Englisch.
Herausgegeben von David G. White, Michael N. Alekshun, Patrick F. McDermott

August 2005 - gebunden - 570 Seiten


Frontiers in Antimicrobial Resistance: a Tribute to Stuart B. Levy offers a unique examination of the state of antimicrobial and anticancer drug resistance. Written by acknowledged experts who have spent time in Dr. Levy's laboratory or who have otherwise collaborated with him professionally, this new volume is a tribute to Dr. Levy and acknowledges his significant contributions to the field. A state-of-the-art review comprising 40 chapters in seven sections, the book opens with a foreword by Dr. Joshua Lederberg. The body of the text features descriptions of the major mechanisms and the epidemiology of resistance and explores the current policy and education efforts toward maintaining drug efficacy. Special emphasis is placed on those areas where Dr. Levy stimulated scientific advancement through his own research and that of his students, research fellows, and colleagues. The chapters are unified in theme; however, each stands alone in conveying the author's individual perspectives regarding the issue of antimicrobial resistance. Frontiers in Antimicrobial Resistance is a major new resource for infectious disease specialists, medical practitioners, and students interested in a review of the accumulated research on resistance among important clinical pathogens.


Table of Contents Foreword, Joshua Lederberg Preface, Stuart B. Levy I. Tetracyclines and Resistance Introduction: Michael N. Alekshun 1. Tetracycline Resistance: Efflux, Mutation, and Other Mechanisms, Frederic M. Sapunaric, Mila Aldema-Ramos, and Laura M. McMurry 2. Tetracycline Resistance Due to Ribosomal Protection Proteins, Marilyn C. Roberts 3. Discovery and Industrialization of the Therapeutically Important Tetracyclines, Mark L. Nelson and Steven J. Projan II. Single Antimicrobial Resistance Mechanisms Introduction: Patrick F. McDermott 4. Fluoroquinolone Resistance, Jordi Vila 5. Beta-Lacatam Resistance in the 21st Century, George Jacoby and Karen Bush 6. Macrolide, Lincosamide, Steptogramin, Ketolide, and Oxazolidinone Resistance, Marilyn C. Roberts and Joyce Sutcliffe 7. Aminoglycoside Resistance Mechanisms, David D. Boehr, Ian F. Moore, and Gerard D. Wright 8. Glycopeptide Resistance in Enterococci, Florence Depardieu and Patrice Courvalin 9. Phenicol Resistance, Stefan Schwarz and David G. White III. Multiple Antimicrobial Resistance Mechanisms Introduction: Patrick F. McDermott 10. Multiple Antimicrobial Resistance, Anthony M. George 11. Metal Resistance Loci of Bacterial Pathogens, Anne O. Summers 12. Biocides and Resistance, Bonnie Marshall and Laura M. McMurry (Appendix: Merri C. Moken) 13. The Nexus of Oxidative Stress Responses and Antibiotic Resistance Mechanisms in Escherichia coli and Salmonella, Bruce Demple 14. The mar Locus, Thamarai Schneiders, Herbert Hachler, and William Yan 15. The mar Regulon, Teresa M. Barbosa and Pablo J. Pomposiello 16. Identificaion of Mar Mutants among Clinical Bacterial Isolates, JoAnn Dzink-Fox and Margret Oethinger 17. Structure and Function of MarA and Its Homologs, Robert G. Martin and Judah L. Rosner 18. Function and Structure of MarR Family Members, Michael N. Alekshun and James F. Head 19. Role, Structure, and Function of Multidrug Efflux Pumps in Gram-Negative Bacteria, Hiroshi Nikaido 20. Role of Mulitdrug Efflux Pumps in Gram-Positive Bacteria, Glenn W. Kaatz IV. Antimicrobial Resistance in Select Pathogens Introduction: David G. White 21. Advances in Vancomycin Resistance: Research in Staphylococcus aureus, Keiichi Hiramatsu, Maria Kapi, Yutaka Tajima, Longzhu Cui, Suwanna Trakulsomboon, and Teruyo Ito 22. Enterococcus, Roland Leclercq and Patrice Courvalin 23. Streptococcus pneumoniae, Joyce Sutcliffe and Marilyn C. Roberts 24. Helicobacter and Campylobacter, Patrick F. McDermott and Diane E. Taylor 25. Anaerobes, Isabelle Podglajen, Jacques Breuil, and Ekkehard Collatz 26. Pseudomonas aeruginosa, Keith Poole 27. Antibiotic Resistance in Salmonella and Shigella, E. J. Threlfall 28. Antibiotic Resistance in Escherichia coli, Mark A. Webber and Laura J. V. Piddock 29. Epidemiology and Treatment Options for Select Community-Acquired and Nosocomial Antibiotic-Resistant Pathogens, John E. Gustafson and John D. Goldman 30. Drug-Resistant Falciparum Malaria: Mechanisms, Consequences, and Challenges, Karen Hayton, Rick M. Fairhurst, Bronwen Naude, Xin-zhuan Su, and Thomas E. Wellems 31. Antimicrobial Susceptibility Testing of Bacterial Agents of Bioterrorism: Strategies and Considerations, Fred C. Tenover V. Ecology and Fitness of Drug Resistance Introduction: David G. White 32. Fitness Traits in Soil Bacteria, Fabrice N. Gravelat, Stephen R. Strain, and Mark W. Silby 33. Ecology of Antibiotic Resistance Genes, Abigail A. Salyers, Hera Vlamakis, and Nadja B. Shoemaker 34. Resistance in the Food Chain and in Bacteria from Animals: Relevance to Human Infections, Vincent Perreten 35. Antimicrobial Use in Plant Agriculture, Anne K. Vidaver VI. Drug Resistance in Cancer Cells Introduction: Michael N. Alekshun 36. Mechanisms of Resistance to Anticancer Agents, Michael P. Draper, Graham K. Jones, Christopher J. Gould, and David E. Modrak 37. Development of Resistance to Anticancer Agents, David E. Modrak, Graham Jones, and Michael P. Draper VII. Policy, Education, and Exploration Introduction: Michael N. Alekshun Commentary. The Birth of the Alliance for the Prudent Use of Antibiotics (APUA), Ellen Koenig 38. Alliance for the Prudent Use of Antibiotics: Scientific Vision and Public Mission, Kathleen T. Young and Thomas F. O'Brien 39. Antimicrobial Use in Animals in the United States: Developments in Policy and Practice, Stephen J. DeVincent and Christina Viola 40. From Perplexing Proteins to Paratek Pharmaceuticals: One Scientific Front Forged by Stuart B. Levy, Mark L. Nelson and S. Ken Tanaka Afterword. Learning and Teaching: a Personal Reflection, Julian Davies Concluding Remarks, Jay A. Levy
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