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Polymeric Drugs and Drug Delivery Systems

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Covering a broad spectrum of methods of drug delivery and focusing on the use of polymers and materials, this volume presents new materials and methods for controlled drug release. Emphasizing selection of materials for drug delivery rather than just … weiterlesen
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Produktdetails

Titel: Polymeric Drugs and Drug Delivery Systems

ISBN: 0841221057
EAN: 9780841221055
New.
Sprache: Englisch.
Herausgegeben von Richard L. Dunn, Raphael M. Ottenbrite
AMER CHEMICAL SOC

Mai 1991 - gebunden - 313 Seiten

Beschreibung

Covering a broad spectrum of methods of drug delivery and focusing on the use of polymers and materials, this volume presents new materials and methods for controlled drug release. Emphasizing selection of materials for drug delivery rather than just reviewing current methods, the editors challenge researchers to venture into new areas and consider new methods. Included is an examination of recent advances in biodegradable and bioerodible polymer matices for drug delivery. An introductory section of four tutorial chapters ("Biologically Active Polymers," "Polymeric Matrices," "Liposomes," and "Interactions Between Polymeric Drug Delivery Systems and Biological Systems") will be of great value to those just entering the field.

Inhaltsverzeichnis

Biologically Active Polymers; Polymeric Matrices; Liposomes; Interactions between Polymeric Drug Delivery Systems and Biological Systems: Barriers and Opportunities; PGG-Glucans: A Novel Class of Macrophage-Activating Immunomodulators; A New *b-Glucan-Based Macrophage-Targeted Adjuvant; Fluorescent Labeling of Heparins and Related Polysaccharides: Old Problems and New Solutions; Design of Polysaccharide-5-Fluorouracil Conjugates Exhibiting Antitumor Activities; Methotrexate-*g-Hydrazide and Divinyl Ether-Maleic Anhydride Conjugate: Antitumor Activity in Mice; Succinimidyl Carbonates of Polyethylene Glycol: Useful Reactive Polymers for Preparation of Protein Conjugates; Poly(*a-amino acid)-Drug Conjugates: A Biodegradable Injectable Drug Delivery System; Transcellular Transport of Protein-Polymer Conjugates in Cultured Epithelial Cells: Release of a Protein from Its Polymeric Carrier During Transcytosis; Opportunities for Protein Delivery by Aerosol: Absorption and Retention of Several Synthetic Polypeptides in the Lung; Synthesis and Characterization of Hydrolytically Labile Poly(phosphoester-urethanes); Desaminotyrosyl-Tyrosine Alkyl Esters: New Diphenolic Monomers for the Design of Tyrosine-Derived Pseudopoly(amino acids); Kinetics of Controlled Release from Acid-Catalyzed Matrices; Bicontinuous Controlled-Release Matrices Composed of Poly(D,L-lactic acid) Blended with Ethylene-Vinyl Acetate Copolymer; Amphiphilic Networks: Synthesis and Characterization of and Drug Release from Poly (N,N-dimethylacrylamide)-1-polyisoburylene; Amphiphilic Networks: Synthesis and Characterization of and Drug Release from Poly(2-hydroxyethyl methacrylate)-1-polyisobutylene; Cross-linked Polyacid Matices for Oral Drug Delivery; Gastric Retention of Enzyme-Digestible Hydrogels in the Canine Stomach under Fasted and Fed Conditions: Preliminary Analysis Using New Analytical Techniques; Cubic Phases as Delivery Systems for Peptide Drugs; Lipid Microspheres and Lecithinized-Polymer Drug Delivery Systems; Drug Delivery by Organ-Specific Immunoliposomes; Novel Polymerized Vesicles with Hydrolyzable Linkages

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