This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
Inhaltsverzeichnis
Catalysis. - Emergence and Evolution. - Architecture. - Protein-protein Interactions and Multicomponent Complexes. - Interactions with RNAs. - Secretion and Circulation. - Regulatory Roles. - Neural Diseases. - Cancer. - Immune Diseases. - Pathologic Implications of Mitochondrial tRNA Synthetases . - Infectious Diseases. - Reprogramming of Genetic Code. - Novel functions of tRNAs. - Perspectives for Systems and Synthetic Bio-Medicine.
