There are more than 100 types of cancers In Part II, head and neck cancer is d- affecting all parts of the human body. cussed. The global number of annual new More than 11 million people are diagnosed cases of this malignancy is ~500, 000. These with cancer every year, and it is estimated malignancies include oral squamous cell that there will be 16 million new cases by carcinoma, salivary gland tumors, tons- the year 2020. In 2005, 7. 6 million peo- lar cancer, tongue cancer, nasopharyngeal ple died of cancer, that is, 13% of the 58 carcinoma, and retinoblastoma, which are million deaths worldwide. It is estimated detailed. In Part III, diagnosis, therapy, and that 9 million people will die from can- prognosis of thyroid carcinoma are d- cer worldwide in 2015 and 11. 4 million cussed. The global number of new cases of will die in 2030. More than 70% of all thyroid cancer is ~141, 000, and the number cancer deaths occur in low and middle of worldwide thyroid mortalities is ~35, 375. income countries. These statistics underlie The number of new cases of this cancer in the fact that cancer is the deadliest of all the United States is ~33, 550. Molecular human diseases. The enormity of the glo- genetics of thyroid cancer, gene expr- bal healthcare costs as a result of cancer sion markers for diagnosis, papillary t- cannot be overemphasized.
Inhaltsverzeichnis
General Methods and Overviews. - Role of RNA Interference in Understanding the Molecular Basis of Cancer. - Cancer Biomarkers (An Overview). - Tumor Angiogenesis in Cancers: Expression of CD105 Marker. - Spindle Cell Oncocytoma of the Adenohypophysis: Integrated Clinicopathologic Diagnosis by Imaging, Histology, and Immunohistochemistry. - Disseminated Carcinoma of Unknown Primary Site: Detection with F-Fluorodeoxyglucose-Positron Emission Tomography. - Unknown Lymphadenopathy: Diagnosing Using an Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsy. - Pretargeted Radioimmunotherapy in Cancer: An Overview. - Chemotherapy-Induced Neurotoxicity. - Multidrug Resistance. - Role of Antibodies in Cancer Treatment (An Overview). - Incorporating Pharmacogenomics into Cancer Therapy. - Cancer Stem Cells: An Overview. - Translating In Vitro Cell Lines Result into Clinical Practice. - Classification of Cancer Stage Using Patient s Immune System. - Late Relapse of Germ Cell Malignancies: Incidence, Management, and Prognosis. - Head and Neck Cancer. - Head and Neck Squamous Cell Carcinoma: Therapy with Fusaric Acid/Paclitaxel. - Early Stage Oral Squamous Cell Carcinoma: Use of Signal Transducer and Activator of Transcription 3 as a Risk Factor for Poor Diagnosis. - Salivary Gland Tumors: Preoperative Tissue Characterization with Apparent Diffusion Coefficient Mapping. - Role of Human Papillomavirus in Tonsillar Cancer. - Quantitative Reverse Transcription Polymerase Chain Reaction Based Assessment of the Candidate Biomarkers for Tongue Cancer Metastasis. - Nasopharyngeal Carcinoma (Retropharyngeal Lymph Node Metastasis): Spread Pattern, Prognosis, and Staging. - Retinoblastoma: Diagnosis, Treatment and Prognosis. - Thyroid Carcinoma. - Molecular Genetics of Thyroid Cancer. - Thyroid Cancer:Identification of Gene Expression Markers for Diagnosis. - Papillary Thyroid Carcinoma: Use of HBME1 and CK19 as Diagnostic Markers. - Papillary Thyroid Carcinoma: Detection of Copy Gain of Platelet Derived Growth Factor B Using Array Comparative Genomic Hybridization in Combination with Laser Capture Microdissection. - PET Imaging in Thyroid Carcinoma. - Metastasized Medullary Thyroid Carcinoma: Detection and Therapy Using Radiolabeled Gastrin Analogs. - Medullary Thyroid Carcinoma: Prognosis based on Stage of Disease and Age. - Overexpression of the Components of the Plasminogen Activating System as Prognostic Factors in Human Thyroid Carcinoma.