Here is the first effort in a single volume to cover all of the integrative functions of calcium signalling - how changes in intracellular calcium coordinate a variety of coherent cellular responses. Written by a team of internationally established researchers, Integrative Aspects of Calcium Signalling provides the latest experimental data and concepts, bringing together a detailed analysis of the events, processes, and functions regulated by calcium signalling. A unique resource for professionals and students of physiology, biophysics, neurobiology, biochemistry, and all related fields.
Inhaltsverzeichnis
Introduction: Principles of Calcium Signalling. - One: Calcium Regulation of Cellular Systems. - 1. The Fate of Calcium Ions Entering a Cell: Calcium Transport through Organelles. - 2. Calcium Regulation of Cytosolic Enzymes. - 3. Function of Nuclear and Cytoplasmic Calcium in the Control of Gene Expression. - 4. Calcium Regulation of Ion Channels. - 5. Modulation of NMDA Receptor Channels by Intracellular Calcium. - 6. Regulation of InsP3R by Ca2+ and Cytosolic Ca2+ Dynamics. - 7. Regulation of Ca2+-Release Channels by Luminal Ca2+. - 8. Mitochondrial Ca2+ Signalling. - 9. Modulation of the Cytoskeletal Architecture by Calcium: A Putative Role in Plastic Synapses. - Two: Calcium Regulation of Cellular Functions. - 10. Calcium and Exocytosis. - 11. Calcium and Neuronal Development and Growth. - 12. Calcium and Cellular Death. - 13. Calcium-Dependent Signalling in Apoptosis. - 14. The Spatial Range of Dendritic Signals for Cerebellar Long-Term Depression: Studies with Local Photolysis of Caged Compounds. - 15. Calcium and Activity-Dependent Synaptic Plasticity. - 16. Ca2+ Waves as a Form of Glial Excitability. - 17. Local Control in Calcium Signalling during Cardiac E-C Coupling.