Titel: Nanotechnology Applications for Tissue Engineering
William Andrew Publishing
8. Januar 2015 - gebunden - 336 Seiten
Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue.Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineering and regenerative medicine. It provides information on methodologies for designing and using biomaterials to regenerate tissue, on novel nano-textured surface features of materials (nano-structured polymers and metals e.g.) as well as on theranostics, immunology and nano-toxicology aspects. In the book also explained are fabrication techniques for production of scaffolds to a series of tissue-specific applications of scaffolds in tissue engineering for specific biomaterials and several types of tissue (such as skin bone, cartilage, vascular, cardiac, bladder and brain tissue). Furthermore, developments in nano drug delivery, gene therapy and cancer nanotechonology are described.The book helps readers to gain a working knowledge about the nanotechnology aspects of tissue engineering and will be of great use to those involved in building specific tissue substitutes in reaching their objective in a more efficient way. It is aimed for R&D and academic scientists, lab engineers, lecturers and PhD students engaged in the fields of tissue engineering or more generally regenerative medicine, nanomedicine, medical devices, nanofabrication, biofabrication, nano- and biomaterials and biomedical engineering.
1. Nanomedicine and Tissue Engineering 2. Design of biomaterials using nanotechnlogy 3. Electrospinning of polymers for tissue engineering. 4. Biomimetic nanofibers for muskuloskeletal tissue engineering 5. Hydrogels - Promising candidates for tissue engineering 6. 3D scaffolding for pancreatic islet replacement 7. Scaffolds with antibacterial properties 8. Dermal tissue engineering: Current trends 9. Chitosan and its application as tissue engineering scaffolds 10. Cell encapsulation in self-assembled hydrogel matrix 11. Nanotechnology enabled drug delivery for cancer therapy 12. Nanomedicine in Theranostics 13. Upconversion nanoparticles 14. Gold nanoparticles for cancer drug delivery 15. Role of nanogenotoxicology studies in safety evaluation of nanomaterials 16. Toxicology considerations in nanomedicine 17. Future of nanotechnology in tissue engineering
Professor Sabu Thomas is Professor of Polymer Science & Engineering, School of Chemical Sciences and the Director of Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University, India. He was the founder Director of the Polymer Engineering program at the School of Technology and Applied Sciences at the Mahatma Gandhi University. Prof. Thomas has published 420 international papers with 6122 total citations. He has 2 patents and 18 books to his credit. He has been a visiting professor at many polymer research laboratories in Europe and Asia. Professor Yves Grohens is the Director of the LIMATB (Material Engineering) Laboratory of Universit de Bretagne Sud, France. His master's and PhD degrees were from Besan on University, France. After finishing his studies, he worked as assistant professor and later professor in various reputed universities in France. He is an invited professor to many universities in different parts of the world as well. His areas of interest include physicochemical studies of polymer surfaces and interfaces, phase transitions in thin films confinement, nano and bio composites design and characterization, and biodegradation of polymers and biomaterials. He has written several book chapters, monographs, and scientific reviews and has published 130 international publications. He is the chairman and member of advisory committees of many international conferences. Dr.Neethu Ninan was awarded PhD in Materials Engineering from Universite de Bretagne Sud, Lorient, France. She received Masters in Engineering in 'Nanotechnology in Medical Science' from Amrita Centre for Nanosciences, Kochi, India. She did her Bachelors of Engineering in 'Biotechnology and Biochemical Engineering'. She worked in collaboration with Universiti Technologi Mara (Malaysia), Mahatma Gandhi University (India) and Chonnam National University (South Korea). She is the editor of four books. She has written several articles, book chapters, and reviews in international journals. Her keen research areas are nanotechnology, composites, tissue engineering, drug delivery and zeolites.