Plant lectins are extensively used as tools and as bioactive proteins in different areas of biomedical and biological research. The Handbook of Plant Lectins provides a comprehensive yet concise overview of the biochemical properties, carbohydrate-binding specificity, biological activities and applications of most of the currently known plant lectins. This handbook consists of two major sections: an introductory guide and a quick reference dictionary. Part I acquaints the newcomer to the lectin field with the essential information on lectins and their importance to biomedicine:
- what are lectins?
- their carbohydrate-binding specificity
- effects on nutrition and immunology
- use in histochemistry
- application as therapeutic agents
Part II lists approximately 200 lectin entries in alphabetical order. Each entry deals with the lectin(s) of a particular plant and provides, (where known), details of:
- isolation and characterisation;
- sugar binding specificity;
- biological activities;
- applications;
- commercial availability; and,
- a bibliography.
Useful summary tables list lectins according to their specificity, thereby allowing the user to choose the best lectin for their application. A list of suppliers is also provided. Handbook of Plant Lectins will be of interest to biologists and biomedical researchers studying cell biology, cancer research, nutrition, immunology, pathology and physiology.
Inhaltsverzeichnis
PART 1: INTRODUCTION TO LECTINS;
PLANT LECTINS: A SPECIAL CLASS OF PLANT PROTEINS: General Considerations About Plant Lectins;
Structure and Evolution of Plant Lectin Genes and Their Genes;
Classification and Nomenclature of Plant Lectins;
PLANT LECTINS IN MAMMALIAN NUTRITION, IMMUNOLOGY, METABOLISM AND AS ORAL THERAPEUTIC AND IMMUNE AGENTS: Introduction;
Lectin-Gut Interactions;
Modification of Epithelial Cell Glycosylation by Lectins;
Effect of Lectins on Gut Bacteria;
Systemic Effect of Lectins;
Lectins as Reagents in Immunology;
Lectins in the Identification and Separation of Lymphoid Cells;
Lectins as Immune Drugs;
LECTINS AS ORAL THERAPEUTIC AGENTS;
LECTIN HISTOCHEMISTRY IN HISTOLOGY AND HISTOPATHOLOGY: Carbohydrate Recognition in Tissue Sections;
Reverse Lectin Histochemistry and Neoglycoproteins;
PART 2: LECTIN CLASSIFICATION;
KEY TO THE USE OF LECTIN ENTRIES;
LECTIN ENTRIES;
Appendix A Classification Codes;
Appendix B Classification Of Lectins Into Lectin Groups;
Appendix C Classification Of Lectins According To Sugar Specificity;
Appendix D Sugar Structures Of Blood Group Antigens;
Appendix E Other Plant Species In Which Haemaeglutinating Activity Was Reported, But The Protein Not Purified;
Appendix F List Of Suppliers.
