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This book provides systematic expert summaries of normal white matter morphology and details white matter injury following stroke and other CNS injuries. It features key notes and implementation advice from the experts.
White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event. The proposed book will be the first to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries.
Inhaltsverzeichnis
White matter: Basic principles of axonal organization and function. - Electrophysiology evaluation of white matter injury. - CADASIL and animal models. - Neuroimaging of White Matter Injury: A Multimodal Approach to Vascular Disease. - Diffusion MRI Biomarkers of White Matter Damage in Traumatic Brain Injury. - Mechanisms underlying the selective vulnerability of developing white matter. - Neonatal experimental white matter injury. - Focal ischemic white matter injury in experimental models. - Global ischemic white matter injury in patients. - Experimental global ischemia and white matter injury. - White Matter Injury after Experimental Intracerebral Hemorrhage. - White Matter Repair after Ischemic Injury. - White Matter Injury in Subarachnoid Hemorrhage in Humans. - Neurodegenerative diseases and white matter injury in patients. - Unmyelinated and myelinated axons exhibit differential injury and treatment response following traumatic brain injury. - Age-Dependent Mechanisms Of White Matter Injury After Stroke. - White matter damage in multiple sclerosis. - Calcium dyshomeostasis in white matter injury. - Inflammation and white matter injury in animal models of ischemic stroke. - Oxidative stress in white matter injury. - Acute Axonal Injury in White Matter Stroke. - Mitochondria disorder and white matter injury. - Heave metal and white matter injury. - Anesthesia and white matter injury.
Produktdetails
Erscheinungsdatum
23. August 2016
Sprache
englisch
Auflage
Softcover reprint of the original 1st edition 2014
Seitenanzahl
608
Reihe
Springer Series in Translational Stroke Research
Herausgegeben von
Selva Baltan, S. Thomas Carmichael, Carlos Matute, Guohua Xi, John H Zhang
Illustrationen
XVI, 592 p. 126 illus., 81 illus. in color.
Verlag/Hersteller
Produktart
kartoniert
Abbildungen
XVI, 592 p. 126 illus., 81 illus. in color.
Gewicht
908 g
Größe (L/B/H)
235/155/33 mm
Sonstiges
Previously published in hardcover
ISBN
9781493953455
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Pressestimmen
From the reviews:
This is an excellent text concerning white matter and the ischemic penumbra of focal cerebral ischemia. This is a very recent review of the literature about inflammatory mediators of injury such as the interleukins, prostaglandins, granulocyte chemotactic factor, and biochemical signal transduction agents. It ties all this information concerning the pathophysiology with autophagocytosis involving membrane proteins, like the chaperones molecules, and lysosomes. I would recommend this book for neurologists, neurosurgeons, students, ischemia researchers, and physiologists. (Joseph J. Grenier, Amazon. com, May, 2014)
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