This e-book consists of the extended high quality papers presented at the 16th International Conference on Information Integration and Web-based Applications & Services (iiWAS2014) in Hanoi, Vietnam. iiWAS is the leading international conference series for researchers and industry practitioners to share their new ideas, original research results and practical development experiences from all information integration and web-based applications & services related areas. The 6 papers included in this e-book were selected from 37 papers presented at the conference. Each paper was extended to include new material to show clear motivation, comprehensive related work, and significant proposal with extensive performance evaluation and/or implementation results.