The definitive guide to the basic principles and latest advances in
Nutritional Genomics
Though still in its infancy, nutritional genomics, or
"nutrigenomics," has revealed much about the complex interactions
between diet and genes. But it is in its potential applications
that nutrigenomics promises to revolutionize the ways we manage
human health and combat disease in the years ahead. Great progress
already has been made in modeling "personalized" nutrition for
optimal health and longevity as well as in genotype-based dietary
interventions for the prevention, mitigation, or possible cure of a
variety of chronic diseases and some types of cancer.
Topics covered include:
* Nutrients and gene expression
* The role of metabolomics in individualized health
* Molecular mechanisms of longevity regulation and calorie
restriction
* Green tea polyphenols and soy peptides in cancer prevention
* Maternal nutrition and fetal gene expression
* Genetic susceptibility to heterocyclic amines from cooked
foods
* Bioinformatics and biocomputation in nutrigenomics
* The pursuit of optimal diets
Written by an all-star team of experts from around the globe, this
volume provides an integrated overview of the cutting-edge field of
nutritional genomics. The authors and editors lead an in-depth
discussion of the fundamental principles and scientific
methodologies that serve as the foundation for nutritional genomics
and explore important recent advances in an array of related
disciplines. Each self-contained chapter builds upon its
predecessor, leading the reader seamlessly from basic principles to
more complex scientific findings and experimental designs.
Scientific chapters are carefully balanced with those addressing
the social, ethical, regulatory, and commercial implications of
nutrigenomics.