HOX Gene Expression

The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. " Hox Gene Expression" starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes- their evolution, structure, normal and abnormal function. Researchers and graduate students in Biology and Medicine will benefit from this integrated overview of Hox gene activities.

The Homeobox as a Key for Understanding the Principles of the Genetic Control of Development. - Expression of Hox Genes in the Nervous System of Vertebrates. - The Hox Gene Network in Vertebrate Limb Development. - Evolution of Hox Gene Clusters. - Evolutionary Genomics of Hox Gene Clusters. - Chromatin and the Control of Hox Gene Expression. - Homeobox-Containing Genes in Limb Regeneration. - Hox Genes and Stem Cells. - Deregulation of the Hox Gene Network and Cancer.