Ovarian Hyperstimulation Syndrome (OHSS) Free Clinic

The book presents a comprehensive guide to eliminating ovarian hyperstimulation syndrome (OHSS) from assisted reproduction. This first-of-its-kind volume unites global experts from Israel, India, Turkey, and Italy to deliver a step-by-step clinical algorithm for safer, patient-centered IVF.

The book explores OHSS from every angle pathophysiology, prediction, prevention, and rescue, while introducing cutting-edge strategies such as metformin use, luteal phase modifications, freeze-all protocols, and in-vitro maturation (IVM). It evaluates the relevance of HCG triggers and presents emerging pharmacological solutions that reshape modern stimulation practices.

Clinicians gain practical tools, visual aids, and evidence-based insights to minimize risk and maximize outcomes. The final chapter synthesizes two decades of research into a visionary protocol for OHSS-free IVF worldwide.

With contributions from renowned figures like Eitan Lunenfeld, Raoul Orvieto, Shahar Kol, Kemal Ozgur, and Andrea Borini, this book serves as both a hands-on manual and an authoritative reference for ART professionals committed to advancing reproductive medicine without compromise.

1. Pathophysiology of OHSS Is it always iatrogenic? . - 2. Current concepts, etiopathology & staging of OHSS. - 3. Prediction & risk-factors of OHSS. - 4. Primary & Secondary OHSS. - 5. Role of counseling in an OHSS-free clinic. - 6. Role of ovarian markers in prevention of OHSS. - 7. Can newer biochemical markers prevent OHSS? . - 8. Role of ultrasound in the prediction & prevention of OHSS. - 9. Current status of metformin in OHSS prevention. - 10. Tweaking follicular phase stimulation protocols for prevention of OHSS. - 11. Luteal phase strategies to prevent OHSS. - 12. Interventional rescue strategies for unexpected OHSS. - 13. Is HCG trigger history? . - 14. The Role of Ultrasound in minimizing morbidity in OHSS. - 15. Is IVM still relevant for an OHSS free clinic? . -16. Newer drugs, interventions & strategies for an OHSS. - 17. Freeze-all for all is the way ahead. - 18. Is there an ideal stimulation protocol for an OHSS-free clinic? .