Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This book describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.
Inhaltsverzeichnis
List of Contents. - Antibody Interactions with Rhinovirus: Lessons for Mechanisms of Neutralizationand the Role of Immunity in Viral Evolution. - Structural Studies on Antibody Interacting with Viruses. - Shape and Electrostatic Complementarity at Viral Antigen-Antibody Complexes. - Structural Studies on Viral Escape from Antibody Neutralization. - Affinity, Complementarity, Cooperativity, and Specificity in Antibody Recognition. - Mechanisms of Virus Neutralization by Antibody. - A Model for Neutralization of Viruses Based on Antibody Coating of the Virion Surface. - Antibody-Mediated Enhancement of Viral Disease. - The Role of the Antibody Response in Influenza Virus Infection. - Role of Antibodies in Controlling Alphavirus Infection of Neurons. - Role of Mucosal Antibodies in Viral Infections. - The Role of the Complement System in Virus Infections. - Intrabodies as Antiviral Agents. - T-Bodies as Antiviral Agents.
