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This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models.
Inhaltsverzeichnis
Basic Bone Biology and Physiology
Chapter 1: Bone morphology and organization
Chapter 2: Bone cells
Chapter 3: Local regulation of bone cell function
Chapter 4: Bone modeling and remodeling
Assessment of Bone Structure and Function
Chapter 5: Skeletal imaging
Chapter 6: Skeletal hard tissue biomechanics
Chapter 7: Techniques in histomorphometry
Chapter 8: Skeletal genetics
Skeletal adaptation
Chapter 9: Mechanical adaptation
Chapter 10: Fracture healing
Chapter 11: Craniofacial biology, orthodontics, and implants
Hormonal and Metabolic Effects on Bone
Chapter 12: Skeletal growth and development
Chapter 13: Calcium and phosphate: Hormonal regulation and metabolism
Chapter 14: Nutrition
Chapter 15: Hormonal effects on bone cells
Skeletal disease and treatment
Chapter 16: Metabolic bone diseases
Chapter 17: Pharmaceutical treatments of osteoporosis
"Quite a wide range of biomedical scientists cover basic bone biology and physiology, assessing bone structure and function, skeletal adaptation, hormonal and metabolic effects on bone, and skeletal disease and treatment. Among specific topics are bone modeling and remodeling, skeletal hard tissue biomechanics, skeletal growth and development, hormonal effects on bone cells, and pharmaceutical treatments of osteoporosis." --ProtoView. com, February 2014
"The textbook was designed for a graduate course in basic bone biology at Indiana University, and many of the contributors teach there or nearly universities. Quite a wide range of biomedical scientists cover basic bone biology and physiology, assessing bone structure and function, skeletal adaptation, hormonal and metabolic effects on bone, and skeletal disease and treatment." --Reference & Research Book News, December 2013
"Basic and Applied Bone Biology provides a comprehensive background of bone science and related research techniques. Topics covered include bone physiology, biomechanics, histomorphometry, skeletal imaging, genetics, and fracture healing; in addition, clinical areas such as metabolic bone diseases and the pharmacological treatment of osteoporosis are discussed. The book is concise, clearly written and beautifully illustrated and will be an invaluable source of information for basic and clinical researchers!" --Juliet Compston, Professor of Bone Medicine, University of Cambridge, School of Clinical Medicine and Addenbrooke's NHS Trust, Deptartment of Medicine, Cambridge, United Kingdom
"I have enjoyed instructing graduate students and orthopedic residents in bone physiology but a reoccurring frustration has been the lack of a comprehensive textbook. I was delighted to learn that Drs. Burr and Allen were editing a textbook, Basic and Applied Bone Biology, and found the quality of the presentation to actually exceed my high expectations. The text is very readable and the illustrations informative and exceptionally clear. Based on the diversity of topics I reviewed, this book will be useful for all scientists engaged in bone research as well as students new to the discipline. I look forward to including it in my personal library as well as using it as a textbook!" --Russell T. Turner, PhD, Professor and Director, Skeletal Biology Laboratory, College Of Public Health and Human Sciences, Oregon State University, Oregon, USA
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