Current Perspectives in microRNAs (miRNA)

In this book, many new perspectives of the miRNA research are reviewed and discussed. These new findings provide significant insight into the various mechanisms of miRNAs and offer a great opportunity in developing new therapeutic interventions.

Structures of MicroRNA Precursors. - Small RNA Technologies: siRNA, miRNA, antagomiR, Target Mimicry, miRNA Sponge and miRNA Profiling. - RNA Interference Expression Vectors Based on miRNAs and RNA Splicing. - Recent Application of Intronic MicroRNA Agents in Cosmetics. - MicroRNA Profiling in CNS Tissue Using Microarrays. - MicroRNA and Erythroid Differentiation. - Homeotic miRNAs: From Development to Pathologies. - MicroRNA in Muscle Development and Function. - MicroRNAs and Regenerative Medicine. - Role of mir-302 MicroRNA Family in Stem Cell Pluripotency and Renewal. - Epigenetic Regulation of miRNA in Stem Cells. - Identification of Cellular Targets for Virally-Encoded miRNAs by Ectopic Expression and Gene Expression Profiling. - MicroRNA in Neuropsychiatric Diseases. - Role of Repeat-Associated MicroRNA (ramRNA) in Fragile X Syndrome (FXS). - miRNA and Schizophrenia. - SNPs in microRNA and microRNA Target Sites Associated with Human Cancers. - Expression and Function of microRNAs in Chronic Myeloid Leukemia. - MicroRNAs in Vascular Neointimal Lesion Formation. - microRNA in Cutaneous Wound Healing. - CpG Island Hypermethylation, miRNAs, and Human Cancer. - Microarray Profiling of microRNA Changes in Cells That Express HIV-1 Proteins. - microRNA-Associated Therapies. - The Use of RNAi to Elucidate and Manipulate Secondary Metabolite Synthesis in Plants.