This book covers advances in nanoparticle-based drug delivery systems, along with the aspects needed for a successful and marketable nano-formulation. With advances in synthetic technologies, nanoparticles can be custom made from variety of advanced materials to mimic the bioenvironment and equipped with various targeting and imaging moieties.
After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation.
FEATURES
- Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles
- Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs
- Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers
- Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts
This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.
Inhaltsverzeichnis
1. Introduction to Nanomaterials for Drug Delivery 2. Manufacturing Techniques for Nanoparticles in Drug Delivery 3. Pharmacokinetics of Nanomaterials/Nanomedicines 4. Bioinspired Nano-Formulations: Materials, Approaches, and Applications in Drug Delivery 5D-Printed Nanocrystals for Oral Administration of the Drugs 6. Functional Nanomaterials 7. Trigger-Sensitive Nanoparticle for Drug Delivery. 8. Metal Organic Frameworks for Drug Delivery 9. Graphene and Graphene-Based Nanomaterials: Current Applications and Future Perspectives 10. Nanomaterials for Lungs Targeting 11. Nanostructured Drug Carriers for Nose-to-Brain Drug Delivery: A Novel Approach for Neurological Disorders 12. Carbon Nanotubes in Cancer Therapy 13. Applications of Silica-Based Nanomaterials for Combinatorial Drug Delivery in Breast Cancer Treatment 14. Cationic Gemini Surfactants as Genes and Drug Carriers 15. Stability of Nanomaterials 16. Nanotoxicology and Regulatory Aspects of Nanomaterials and Nanomedicines
