Metabolomics - which deals with all metabolites of an organism - is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology.
This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.
Inhaltsverzeichnis
Analytical Technology. - Gas Chromatography Mass Spectrometry. - Current Status and Forward Looking Thoughts on LC/MS Metabolomics. - Plant Metabolomics Strategies Based upon Quadrupole Time of Flight Mass Spectrometry (QTOF-MS). - Capillary HPLC. - Capillary HPLC Coupled to Electrospray Ionization Quadrupole Time-of-flight Mass Spectrometry. - NMR Spectroscopy in Plant Metabolomics. - Hetero-nuclear NMR-based Metabolomics. - Bioinformatics. - Bioinformatics Approaches to Integrate Metabolomics and Other Systems Biology Data. - Chemometrics in Metabolomics An Introduction. - Map Editor for the Atomic Reconstruction of Metabolism (ARM). - AraCyc: Overview of an Arabidopsis Metabolism Database and its Applications for Plant Research. - KaPPA-View: A Tool for Integrating Transcriptomic and Metabolomic Data on Plant Metabolic Pathway Maps. - KNApSAcK: A Comprehensive Species-Metabolite Relationship Database. - Applications. - Systems Biology: A Renaissance of the Top-down Approach for Plant Analysis. - Systems-based Analysis of Plant Metabolism by Integration of Metabolomics with Transcriptomics. - Targeted Profiling of Fatty Acids and Related Metabolites. - Metabolic Profiling and Quantification of Carotenoids and Related Isoprenoids in Crop Plants. - Metabolomics and Gene Identification in Plant Natural Product Pathways. - Metabolomic Analysis of Catharanthus roseus Using NMR and Principal Component Analysis. - Metabolomics of Plant Secondary Compounds: Profiling of Catharanthus Cell Cultures. - The Taxus Metabolome and the Elucidation of the Taxol® Biosynthetic Pathway in Cell Suspension Cultures. - The Use of Non-targeted Metabolomics in Plant Science. - Plant Metabolite Profiling for Industrial Applications.