This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia. The event is held every four years in a different country and for the Yersinia 2010, an interesting and updated program covering advances in research in Yersiniae was organized. The major advances achieved over the past four years since the last symposium held in Lexington, USA in 2006 were divided into eight chapters: Epidemiology, Clinical, Diagnostic and Therapeutic aspects; Ecology and Modeling; Genomic/Transcriptomics and Large Scale Population; Immune Response and Vaccine; Pathogenesis and Pathogenicity Factors; Cellular Yersiniology; Bacterial Structure and Metabolism: Roles in Pathogenesis and Bacterial Life Style. The purpose of the book is to extend cutting edge knowledge on Yersinia discussed during the 10th International Symposium.
Inhaltsverzeichnis
Evolutionary dynamics of the
Yersinia enterocolitica. -
Gains and losses in
Yersinia enterocolitica
subsp
. palearctica
genomes. - Consequences of Missense Mutations in
Yersinia pestis
: Efficient flow of Metabolic Carbon versus Virulence. - Diversity and adaptive evolution of major porin gene (
ompF
) in
Yersinia pseudotuberculosis. -
Biochemical and Genetic Peculiarities and the Phylogenetic Relationship of the Non-main Subspecies in the General Scheme of the Plague Agent Evolution. - The molecular phylogeny of
gyrB
gene: a molecular marker for systematic of
Yersinia. -
Preliminary survey regarding Yersiniosis in Ireland. - Pseudotuberculosis in Russian Federation. - Plague in Brazil: now and then. - Factors Affecting the Spread and Maintenance of Plague. - Isolation of enteropathogenic
Yersinia
from non-human sources. - Yersiniosis by
Yersinia pseudotuberculosis
o iii causes diarrhea in Brazilian cattle. - Prevalence, Serotype, Virulence characteristics, Clonality and Antibiotic susceptibility of pathogenic
Yersiniaenterocolitica
from swine feces. - Characterization of
Yersinia enterocolitica
4/O:3 isolated from swine in slaughterhouses and pork in State of São Paulo. - Bacteriophages capable of lysing
Yersinia pestis
and
Yersinia pseudotuberculosis:
efficiency of plating tests and identification of receptors in
Escherichia coli
K-12. - Field and clinical applications of advanced bacteriophage-based detection of
Yersinia pestis. - Plague diagnosis STNPCR and M-PCR kits assembly, reaction reproducibility and reagent stability. -
Innate immune responses during infection with
Yersinia pestis. -
The life stage of
Yersiniapestis
in the flea vector confers resistance to host polymorphonuclear leukocyte phagocytosis and killing. - Phagocytes and humoral immunity to pneumonic plague. - In vitro evaluation of antiplague cellular immunity by quantitative analysis of IFN- synthesis and appearance of activation molecules on the surface of T-helpers. - Cytotoxic necrotizing factor is an effective immunogen in a
Yersinia pseudotuberculosis
aerosol mouse model. - Fimbrial polyadhesins: anti-immune armament of
Yersinia. -
Yop effector proteins from
Yersinia pseudotuberculosis
impair dendritic cells activation. - Impact on the host of the
Yersinia pestis
specific virulence set and contribution of the Pla surface protease. - Virulence of
Yersinia pseudotuberculosis
in aerosol models. - Pathogenic potential of
Yersinia massiliensis
species. - Modulation of host cell death pathways by
Yersinia
and the type three secretion effector YopK. - Biofilm-dependent and biofilm-independent mechanisms of transmission of
Yersinia pestis
by fleas. - YopM and Plague. - Substrates of the plasminogen activator protease of
Yersinia pestis. -
Variability of the functional domains of the Rho-modifying toxins of
Yersinia pseudotuberculosis. - Yersinia pestis
transition metal divalent cation transporters. - Unique virulence properties of
Yersinia enterocolitica
O:3. -
Yersinia pestis
autoagglutination is mediated by hcp-like protein and siderophore Yersiniachelin. -
Yersinia
surface structures and bacteriophages. - Global discovery of small non-coding rnas in pathogenic
Yersinia
species. - Regulation of virulence gene expression by regulatory RNA elements in
Yersinia pseudotuberculosi
s. - OmpR, a central integrator of several cellularresponses in
Yersinia enterocolitica. -
Bacteriophage therapy of experimental bubonic plague in mice. - Preliminary pharmacokinetics of the bacterial virulence inhibitor N' -(3, 5-dibromo-2-hydroxy-benzylidenene)-nicotinic acid hydrazide. - Small molecule screening for inhibitors of the YopH phosphatase of
Yersinia pseudotuberculosis.