Brain Protection in Cardiac Surgery

Part of the Monographs in Cardiac Surgery Series - Introducing 'basic science into the cardiac operating room'. Fast systematic review of small areas of cardiac surgery including up-to-date information. This will allow more rapid publication than the alternative cardiac surgery 'tomes'. This entry into the series will provide readers with a complete review of the current understanding in brain injury and the methods used to avoid or limit its effects on patient morbidity and mortality.

Brain injury of cardiac surgery. -
Cerebral physiology & metabolism. -Molecular & biochemical basis. Future interventions. -Cardiopulmonary bypass circuit. -Neurological sequelae. -Incidence, pre-operative risk factors & long-term outcome. -Neuropathology. -Inflammatory response. -Post-surgical impact. -
Assessment of brain injury. -
Utility of neuropsychometric analysis. -Pitfalls of neuropsychometric assessment & alternative investigative approaches. -Imaging of the brain. -Current techniques of emboli detection. -Intra-operative brain monitoring. -Design of brain protection studies in the C21st. -
Reducing brain injury in cardiac surgery. -
Temperature & brain protection. -Studies of non-pharmacological interventions. -Pharmacological studies to reduce brain injury following cardiac surgery. -Off-pump & on-pump coronary artery surgery & the brain. -Experimental basis & clinical studies of brain protection in paediatric heart surgery. -Experimental basis & clinical studies of brain protection in aortic arch surgery. -
The future.