This book introduces the concepts and practical tools necessary to understand the behavior of biological macromolecules at a quantitative level, going beyond theory to explain in detail how the equations are applied to the analysis of experimental measurements. An emphasis on real-world applications is a continued throughout the book.
Inhaltsverzeichnis
Series Preface
Preface
Acknowledgments
Note to Instructors
Author
Chapter 1 Probabilities and Statistics in Chemical and Biothermodynamics
Chapter 2 Mathematical Tools in Thermodynamics
Chapter 3 The Framework of Thermodynamics and the First Law
Chapter 4 The Second Law and Entropy
Chapter 5 Free Energy as a Potential for the Laboratory and for Biology
Chapter 6 Using Chemical Potentials to Describe Phase Transitions
Chapter 7 The Concentration Dependence of Chemical Potential, Mixing, and Reactions
Chapter 8 Conformational Equilibrium
Chapter 9 Statistical Thermodynamics and the Ensemble Method
Chapter 10 Ensembles That Interact with Their Surroundings
Chapter 11 Partition Functions for Single Molecules and Chemical Reactions
Chapter 12 The Helix-Coil Transition
Chapter 13 Ligand Binding Equilibria from a Macroscopic Perspective
Chapter 14 Ligand Binding Equilibria from a Microscopic Perspective
Appendix: How to Use Mathematica 485
Bibliography
Index