Opening Remark.- Structural Correlates of Immune Microenvironment.- Session 1 Microenvironmental Aspects of Lymphatic Tissue.- Introduction: Microenvironments in the Lymphoid System.- Differentiation of B Lymphocytes from Stem Cell Precursors.- Hemopoietic Origin of B Cells in the Mouse.- Lymphocyte Differentiation in the Chicken Embryo - Relationship to the Microenvironment.- The Lymphoid Development of the Embryonic Chicken Thymus in Organ Culture.- Colonizing Capacity of Lymphoid Cells Injected into Syngeneic Hosts.- Differential Traffic Patterns of T and B Lymphocytes in Relation to Germinal Centre Development.- Ecotaxis of B Cells in the Mouse.- Homing of B-Lymphocytes to Follicles: Specific Retention of Immunologically Committed Cells.- Antigenic Markers on Lymphoid Cells Varying in Their Capacity to Recirculate.- Thymus Cell Migration: 3HTdR-Labeled and Theta-Positive Cells in Peripheral Lymphoid Tissues of Newborn Mice.- Lymph Node Function and Lymphocyte Circulation in the Pig.- Germinal Centers: A Microenvironment for the Production of Antibody Forming Precursors?.- Microenvironmental Aspects of Lymphatic Tissue: Summary.- Session 2 Interaction of Lymphatic Cells.- Introduction: Cell Cooperation in Antibody Production - A Perspective with Questions.- Functional Heterogeneity of Thymus-Derived Lymphocytes.- Some Cell Surface Properties of Thymus-Derived Lymphocytes in Bursectomized Chickens.- Studies on the Influence of T Cells in Antibody Responses of Mice to SIII and DNP-Lysine-SIII.- Induction of Anti-Hapten Antibody Responses against Haptens Conjugated to Autologous and Heterologous Proteins.- Contribution of B and T Lymphocytes to in vitro Chicken Proliferative Spleen Cell Reactions to Antigens.- Proliferation of Activated Thymocytes in MixedLymphocyte Reactions.- Lymphoid Cell Interactions in Cell-Mediated Immunity.- Appendix and Thymus Cell Synergism in the Direct and Indirect Plaque Forming Cell Response to Sheep Erythrocytes.- The Role of Soluble Factors in T-B Cell Collaboration.- Studies on the Source and Action of the T-Cell Replacing Factor (TRF).- Thymus Extracts Induce Differentiation of Thymus Derived Cells.- Interaction of Lymphatic Cells: Summary.- Session 3 Antigen Recognizing and Processing Cells.- Introduction: Antigen Recognizing and Processing Cells.- Immunoglobulin Surface Determinants on Chicken Lymphoid Cells.- Functional and Morphologic Characteristics of Complement Receptor Lymphocytes in Mice.- Stimulation of Mouse Thymocytes by Syngeneic Spleen Cells in Mixed Lymphocyte Reactions.- Differential Induction and Suppression of Direct and Indirect PFC Responses to TNP Conjugated to Heterologous Erythrocytes.- Reconstitution of Primary Response in vitro by Defined Peritoneal Cells.- Uptake and Degradation of a Synthetic Antigen by Mouse Macrophages Containing Different Levels of Lysosomal Enzymes.- Direct Evidence for Plaque Formation by Macrophages.- The Proportion of Lymphocytes Capable of Recognizing Strong Transplantation Antigens in vivo.- Recovery of the Immune Response after Depletion of Specific Cells.- Early Appearance of Antigen-Binding Cells to Two Different Antigens during Fetal Lymphoid Development.- Antigen Recognizing and Processing Cells: Summary.- Session 4 Cellular Aspects of Immune Deficiency Diseases.- Introduction: Cellular Aspects of Immune Deficiency Diseases Involving B Cells.- Enhancement of the Immune Response of Genetically Thymus-Less Mice by Different Cell Populations.- Thymus Factors and Immunity: Enhancement of Immunologic Maturation by a Purified Calf Thymus Extract.- Involution of the Thymus Dependent Lymphoid System.- A Study on Human T Lymphocytes, Their Function and Frequency in Some Diseases.- Evidence of Two Functionally Distinct Lymphocyte Populations in Man.- The Relation between Nutritional Deprivation and Immunity.- Combined System Immunodeficiency with DiGeorge Syndrome and Dissociation of PHA/MLC Responses.- Transplantation of Haemopoietic Stem Ce
Inhaltsverzeichnis
Opening Remark. - Structural Correlates of Immune Microenvironment. - Session 1 Microenvironmental Aspects of Lymphatic Tissue. - Introduction: Microenvironments in the Lymphoid System. - Differentiation of B Lymphocytes from Stem Cell Precursors. - Hemopoietic Origin of B Cells in the Mouse. - Lymphocyte Differentiation in the Chicken Embryo Relationship to the Microenvironment. - The Lymphoid Development of the Embryonic Chicken Thymus in Organ Culture. - Colonizing Capacity of Lymphoid Cells Injected into Syngeneic Hosts. - Differential Traffic Patterns of T and B Lymphocytes in Relation to Germinal Centre Development. - Ecotaxis of B Cells in the Mouse. - Homing of B-Lymphocytes to Follicles: Specific Retention of Immunologically Committed Cells. - Antigenic Markers on Lymphoid Cells Varying in Their Capacity to Recirculate. - Thymus Cell Migration: 3HTdR-Labeled and Theta-Positive Cells in Peripheral Lymphoid Tissues of Newborn Mice. - Lymph Node Function and Lymphocyte Circulation in the Pig. - Germinal Centers: A Microenvironment for the Production of Antibody Forming Precursors? . - Microenvironmental Aspects of Lymphatic Tissue: Summary. - Session 2 Interaction of Lymphatic Cells. - Introduction: Cell Cooperation in Antibody Production A Perspective with Questions. - Functional Heterogeneity of Thymus-Derived Lymphocytes. - Some Cell Surface Properties of Thymus-Derived Lymphocytes in Bursectomized Chickens. - Studies on the Influence of T Cells in Antibody Responses of Mice to SIII and DNP-Lysine-SIII. - Induction of Anti-Hapten Antibody Responses against Haptens Conjugated to Autologous and Heterologous Proteins. - Contribution of B and T Lymphocytes to in vitro Chicken Proliferative Spleen Cell Reactions to Antigens. - Proliferation of Activated Thymocytes in MixedLymphocyte Reactions. - Lymphoid Cell Interactions in Cell-Mediated Immunity. - Appendix and Thymus Cell Synergism in the Direct and Indirect Plaque Forming Cell Response to Sheep Erythrocytes. - The Role of Soluble Factors in T-B Cell Collaboration. - Studies on the Source and Action of the T-Cell Replacing Factor (TRF). - Thymus Extracts Induce Differentiation of Thymus Derived Cells. - Interaction of Lymphatic Cells: Summary. - Session 3 Antigen Recognizing and Processing Cells. - Introduction: Antigen Recognizing and Processing Cells. - Immunoglobulin Surface Determinants on Chicken Lymphoid Cells. - Functional and Morphologic Characteristics of Complement Receptor Lymphocytes in Mice. - Stimulation of Mouse Thymocytes by Syngeneic Spleen Cells in Mixed Lymphocyte Reactions. - Differential Induction and Suppression of Direct and Indirect PFC Responses to TNP Conjugated to Heterologous Erythrocytes. - Reconstitution of Primary Response in vitro by Defined Peritoneal Cells. - Uptake and Degradation of a Synthetic Antigen by Mouse Macrophages Containing Different Levels of Lysosomal Enzymes. - Direct Evidence for Plaque Formation by Macrophages. - The Proportion of Lymphocytes Capable of Recognizing Strong Transplantation Antigens in vivo. - Recovery of the Immune Response after Depletion of Specific Cells. - Early Appearance of Antigen-Binding Cells to Two Different Antigens during Fetal Lymphoid Development. - Antigen Recognizing and Processing Cells: Summary. - Session 4 Cellular Aspects of Immune Deficiency Diseases. - Introduction: Cellular Aspects of Immune Deficiency Diseases Involving B Cells. - Enhancement of the Immune Response of Genetically Thymus-Less Mice by Different Cell Populations. - Thymus Factors and Immunity: Enhancement of Immunologic Maturation by a Purified Calf Thymus Extract. - Involution of the Thymus Dependent Lymphoid System. - A Study on Human T Lymphocytes, Their Function and Frequency in Some Diseases. - Evidence of Two Functionally Distinct Lymphocyte Populations in Man. - The Relation between Nutritional Deprivation and Immunity. - Combined System Immunodeficiency with DiGeorge Syndrome and Dissociation of PHA/MLC Responses. - Transplantation of Haemopoietic Stem Cell (HSC) Concentrates for Treatment of Immune Deficiency Disease. - Immunological and Clinical Effects of Transfer Factor in Anergic Subjects. - Cellular Aspects of Immune Deficiency Diseases: Summary. - Session 5 Lymphatic Tissue in Tolerance, Immunosuppression and Facilitation. - Introduction: Different Types of Immunological Unresponsiveness. - Mechanism of Antigen Binding to Receptor Antibody in B Cell Immunity and Tolerance in vitro. - Characteristics of B Cell Tolerance Induced with T-Independent Polysaccharides. - Cortisone Interfering with the Production of T and B Cells . - Immunosuppression of the Thymectomized Fetal Lamb and Its Neonatal Reconstitution. - Antigen Recognition and Localization in RES Blockaded Mice: Morphologic and Immunologic Studies. - The Effect of Cyclophosphamide on the Primary Humoral Immune Response. The Immunological Priming. - Germinal Center in Rat Lymphatic Tissues after the Administration of L-Asparaginase. - Enhancement of Tumour Growth by Lymphoid Cells from Mice Treated with Antilymphocyte Globulin. - Role of the Spleen in Immunologic Enhancement of Kidney Grafts in Rats. - Tolerance in Ovum Fusion Derived Tetraparental Mouse in Chimaeras. - Role of IgG1 in Immunological Enhancement Facilitation. - Lymphatic Tissue in Tolerance, Immunosuppression and Facilitation: Summary. - Session 6 Reaction of Lymphatic Tissue in NeoplasticDisease. - Introduction: Immune Reactions to Neoplastic Disease. - Foetal Liver Stem Cells Inhibition by Ehrlich Ascites Carcinoma. - Suppressed Plaque and Rosette-Formation by Spleen Cells of Mice Injected with Tumor Extracts. - Immunosuppressive Factors Associated with Tumors. - Effect of Therapy and Tumour Stage on Cellular Immunity to Bladder Carcinoma. - Phase Specific Surface Autoantigens on Membranes of Fetus and Tumors. - B Cell, T Cell and Monocyte Origin of the Guinea Pig L2C Leukemia, Mouse Lymphomas and Human Leukemias and Lymphoblastic Cell Lines. - Immunocytes and Leukemia Virus Infection: Effects on Bone Marrow and Thymus Cell Responses and Interactions. - Influence of the Lymphatic System on Development of a Virus-Induced Tumor (Reticuloendotheliosis) in the Chicken. - Immune Reactions of the Syngeneic Host after the Intradermal Injection of Tumor Cells and Microsomes. - Enhancement of Metastases by L-Asparaginase in Allogeneic and Isogeneic Mouse Tumor Systems. - Reaction of Lymphatic Tissue in Neoplastic Disease: Summary. - Session 7 Lymphatic Tissue in Immunopathology, with Special Reference to Delayed Hypersensitivity. - Introduction: Interaction between B and T Lymphocytes in Delayed Hypersensitivity. - Contact Sensitivity in the Pig. - The Effect of Lymphatic Interruption and Immediate Vascularization on the Afferent Arc of Skin Graft Rejection. - Homograft Sensitivity in the Mouse: The Periodic Redistribution of Sensitised Lymphoid Cells. - The Onset and Time-Course of Delayed-Type Hypersensitivity in Rats. - Adjuvants and in vitro Antibody Production. - Basophilic Leucocytes in Delayed-Type Hypersensitivity Reactions in Experimental Animals and Man. - Antibody and Cell Requirements for Cytotoxicity by Non-Immune Effector Cells. - The Induction of a Cellular Immune Reaction against Self-Antigens Present in the Thymus. - Germinal Center Formation in Response to Skin Grafted across Weak and Strong Histocompatibility (H2) Barriers. - Thymectomy and Bursectomy in Chickens with Simultaneous Experimental and Spontaneous Autoimmune Disease. - Possible Role of Lymphokines in the Development of Ectopic Lymphoid Foci in the Chicken. - Mediators of Cellular Hypersensitivity and Immunity Including Immunologically Specific Factors. - Lymphatic Tissue in Immunopathology, with Special Reference to Delayed Hypersensitivity: Summary. - Session 8 New Experimental Approaches. - Introduction: New Experimental Approaches. - Manipulation of Fertilised Mouse Eggs Applied to Immunology. - The Use of Germ-Free Piglets in the Study of Lymphoid Tissue and Germinal Centre Formation. - Influence of Thymus on the Development of Endocrine and Immune Functions in Ontogeny. - Hormones and Lymphoid Tissues. Contact Sensitivity and Detection of Theta-Cells in Pituitary Dwarf Mice. - Immune Response and Lymphatic Tissue Reaction in Brain-Lesioned Rats. - Stress and Hormonal Intervention in the Graft-versus-Host Response. - Antibody Responses in Cell Cultures from Draining and Non-Draining Rabbit Lymph Nodes Primed with Native or Polymerized Human Albumin. - Changes in DNA Synthesis During Immunization in Mouse Spleen as Shown by Autoradiographs with Long Exposure Times. - The Specific Separation of Enzyme Antigen-Binding Cells by Substrate Affinity Chromatography. - New Experimental Approaches: Summary. - Invitev Speakers. - Molecular Pharmacology of Cell-Mediated Immunity. - Immuno-Embryology. The Onset of Immunocompetence in Mammals and Birds Integrated by Age-Equivalence.
