Neuroinflammation and Schizophrenia

Preface. - A Brief History of Immunological Research into Psychosis and Pathways for Immune Influence of the Brain. -Basic Concept of Microglia Biology and Neuroinflammation in Relation to Psychiatry. - Epidemiological Studies of Prenatal and Childhood Infection and Schizophrenia. - Schizophrenia, Cytokines and Other Systemic Inflammatory Mediators [to include oxidative stress and lymphocyte alterations]. - Association between Schizophrenia, Microbial Infection and Microbiota. - Autoantibodies and psychosis. - Effect of Infection on Cognition in Schizophrenia and Healthy People. - Role of Infection, Autoimmunity, Atopic Disorders and the Immune System in Schizophrenia: Evidence from Epidemiological and Genetic Studies. - Microglial Activation and Psychotic Disorders: Evidence from Pre-clinical and Clinical Studies. - Early-Life Adversity, Systemic Inflammation, and Co-Morbid Physical and Psychiatric Illnesses of Adult Life. - Inflammation, Antipsychotic Drugs and Evidence for Effectiveness ofAnti-inflammatory Agents in Schizophrenia.