Organic Chemistry, Global Edition

For courses in Organic Chemistry (2-Semester)

A framework for organic chemistry built around the similarities in reaction types

Paula Bruice s presentation in Organic Chemistry, 8th Edition provides mixed-science majors with the conceptual foundations, chemical logic, and problem-solving skills they need to reason their way to solutions for diverse problems in synthetic organic chemistry, biochemistry, and medicine. The 8th Edition builds a strong framework for thinking about organic chemistry by unifying principles of reactivity that students will apply throughout the course, discouraging memorisation. With more applications than any other textbook, Dr. Bruice consistently relates structure and reactivity to what occurs in our own cells and reinforces the fundamental reason for all chemical reactions electrophiles react with nucleophiles. New streamlined coverage of substitution and elimination, updated problem-solving strategies, synthesis skill-building applications and tutorials guide students throughout fundamental and complex content in both the first and second semesters of the course.

For courses in Organic Chemistry (2-Semester)

A framework for organic chemistry built around the similarities in reaction types

Paula Bruice's presentation in Organic Chemistry, Eighth Edition provides mixed-science majors with the conceptual foundations, chemical logic, and problem-solving skills they need to reason their way to solutions for diverse problems in synthetic organic chemistry, biochemistry, and medicine. The Eighth Edition builds a strong framework for thinking about organic chemistry by unifying principles of reactivity that students will apply throughout the course, discouraging memorization. With more applications than any other textbook, Dr. Bruice consistently relates structure and reactivity to what occurs in our own cells and reinforces the fundamental reason for all chemical reactions-electrophiles react with nucleophiles. New streamlined coverage of substitution and elimination, updated problem-solving strategies, synthesis skill-building applications and tutorials guide students throughout fundamental and complex content in both the first and second semesters of the course.

MasteringChemistry^(TM) is not included. Students, if MasteringChemistry is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. MasteringChemistry should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

MasteringChemistry an online homework, tutorial, and assessment program designed to work with this text to engage students and improve results. Interactive, self-paced tutorials provide individualized coaching to help students stay on track. With a wide range of activities available, students can actively learn, understand, and retain even the most difficult concepts.

• PART ONE: An Introduction to the Study of Organic Chemistry
• 1. Remembering General Chemistry: Electronic Structure and Bonding
• 2. Acids and Bases: Central to Understanding Organic Chemistry
• TUTORIAL: Acids and Bases
• 3. An Introduction to Organic Compounds: Nomenclature, Physical Properties, and Structure
• PART TWO: Electrophilic Addition Reactions, Stereochemistry, and Electron Delocalization
• TUTORIAL: Using Molecular Models
• 4. Isomers: The Arrangement of Atoms in Space
• TUTORIAL: Interconverting Structural Representations
• 5. Alkenes: Structure, Nomenclature, and an Introduction to Reactivity Thermodynamics and Kinetics
• TUTORIAL: Drawing Curved Arrows
• 6. The Reactions of Alkenes The Stereochemistry of Addition Reactions
• 7. The Reactions of Alkynes An Introduction to Multistep Synthesis
• 8. Delocalized Electrons: Their Effect on Stability, pKa, and the Products of a Reaction Aromaticity and Electronic Effects: An Introduction the Reactions of Benzene
• TUTORIAL: Drawing Resonance Contributors
• PART THREE: Substitution and Elimination Reactions
• 9. Substitution and Elimination Reactions of Alkyl Halides
• 10. Reactions of Alcohols, Ethers, Epoxides, Amines, and Sulfur-Containing Compounds
• 11. Organometallic Compounds
• 12. Radicals
• TUTORIAL: Drawing Curved Arrows in Radical Systems
• PART FOUR: Identification of Organic Compounds
• 13. Mass Spectrometry; Infrared Spectroscopy; and UV/Vis Spectroscopy
• 14. NMR Spectroscopy
• PART FIVE: Carbonyl Compounds
• 15. Reactions of Carboxylic Acids and Carboxylic Acid Derivatives
• 16. Reactions of Aldehydes and Ketones More Reactions of Carboxylic Acid Derivatives
• 17. Reactions at the -Carbon
• TUTORIAL: Synthesis and Retrosynthetic Analysis
• PART SIX: Aromatic Compounds
• 18. Reactions of Benzene And Substituted Benzenes
• 19. More About Amines Reactions of Heterocyclic Compounds
• PART SEVEN: Bioorganic Compounds
• 20. The Organic Chemistry Of Carbohydrates
• 21. Amino Acids, Peptides, and Proteins
• 22. Catalysis in Organic Reactions and in Enzymatic Reactions
• 23. The Organic Chemistry of the Coenzymes, Compounds Derived from Vitamins
• 24. The Organic Chemistry of the Metabolic Pathways
• 25. The Organic Chemistry of Lipids
• 26. The Chemistry of the Nucleic Acids
• PART EIGHT: Special Topics in Organic Chemistry
• 27. Synthetic Polymers
• 28. Pericyclic Reactions
• Appendix I pKa Values
• Appendix II Kinetics
• Appendix III Summary of Methods Used to Synthesize a Particular Functional Group
• Appendix IV Summary of Methods Employed to Form Carbon-Carbon Bonds
• Appendix V Spectroscopy Tables
• Appendix VI Physical Properties of Organic Compounds
• Appendix VII Answers to Selected Problems