History of a Pioneering Neuropeptide: Substance P.- The Tachykinin Peptide Family, with Particular Emphasis on Mammalian Tachykinins and Tachykinin Receptor Agonists.- The Histochemistry of Tachykinin Systems in the Brain.- The Nomenclature of Tachykinin Receptors.- The Mechanism and Function of Agonist-Induced Trafficking of Tachykinin Receptors.- Tachykinin NK1 Receptor Antagonists.- Tachykinin NK2 Receptor Antagonists.- Tachykinin NK3 Receptor Antagonists.- Combined Tachykinin NK1, NK2, and NK3 Receptor Antagonists.- Pre-protachykinin and Tachykinin Receptor Knockout Mice.- Therapeutic Potential of Tachykinin Receptor Antagonists in Depression and Anxiety Disorders.- The Role of Tachykinins and the Tachykinin NK1 Receptor in Nausea and Emesis.- Substance P (NK1 Receptor Antagonists-Analgesics or Not?.- Role of Tachykinins in Neurogenic Inflammation of the Skin and Other External Surfaces.- Role of Tachykinins in Obstructive Airway Disease.- Role of Tachykinins in the Gastrointestinal Tract.
Inhaltsverzeichnis
History of a Pioneering Neuropeptide: Substance P. - The Tachykinin Peptide Family, with Particular Emphasis on Mammalian Tachykinins and Tachykinin Receptor Agonists. - The Histochemistry of Tachykinin Systems in the Brain. - The Nomenclature of Tachykinin Receptors. - The Mechanism and Function of Agonist-Induced Trafficking of Tachykinin Receptors. - Tachykinin NK1 Receptor Antagonists. - Tachykinin NK2 Receptor Antagonists. - Tachykinin NK3 Receptor Antagonists. - Combined Tachykinin NK1, NK2, and NK3 Receptor Antagonists. - Pre-protachykinin and Tachykinin Receptor Knockout Mice. - Therapeutic Potential of Tachykinin Receptor Antagonists in Depression and Anxiety Disorders. - The Role of Tachykinins and the Tachykinin NK1 Receptor in Nausea and Emesis. - Substance P (NK1 Receptor Antagonists-Analgesics or Not? . - Role of Tachykinins in Neurogenic Inflammation of the Skin and Other External Surfaces. - Role of Tachykinins in Obstructive Airway Disease. - Role of Tachykinins in the Gastrointestinal Tract.