Inhaltsverzeichnis
The L-DOPA story revisited. Further surprises to be expected? . - The enigma of cell death in neurodegenerative disorders. - Impaired iron homeostasis in Parkinson s disease. - The molecular mechanism of dopamine-induced apoptosis: identification and charac te rization of genes that med iate dopamine toxicity. - Glyce raldehyde-3-phosp hate dehydrogenase in neurodegenerat ion and apoptosis signaling. - Import ance of familial Parkinson s disease and parkinsonism to the understand -
ing of nigraI degener at ion in sporadic Parkinson s disease. - cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6 hydroxydopamine models: implications for idiopathic Parkinson s disease. - Moni toring neurop rotection and restorative therapies in Parkinson s disease with PET. - Common properties for prop argylamines of enhancing superoxide dismutase and catalase activities in the dopaminergic system in the rat: implications for the life prolonging effect of ( 2212; )deprenyl. - TV3326, a novel neuro protective dru g with cholinesterase and monoamine oxidase inhibito ry activities for the treatm ent of Alzheimer s disease. - Neurotoxins induce apoptosis in dopamine neurons: prot ection bei N-propargylamine- l(R)- and (5)-aminoi ndan, rasagi line and TV1022. - Homocysteine and alcoholism. - Neur orescuing effects of the GAPDH ligand CGP 34668. - The neuroprotective effects of CGP 34668 in the best in vivo model of Parkinson s disease, the bilaterally MPTP-treated rhesus monke. - Neurotrophic effects of central nicotinic receptor activation. - Regulation of neuronal cell death and differentiation by NGF and IAP family members. - Insulin-like growth factor- 1 (IGF-1): a neuroprotective trophic factor acting via the Aktinase pathway. -GDF-15/MIC-1 a novel member of the TGF-? superfamily. - Changes in cytokines and neurotrophins in Parkinson s disease. - Psychiatric complications in Parkinson s disease. - Dementia with Lewy bodies: prevalance, clinical spectrum and natural history. - Neuronal degeneration and reorganization: a mutual principle in pathological and in healthy interactions of limbic and prefrontal
circuits. - Depression in alpha-synucleinopathies: prevalence, pathophysiology and treatment. - The serotonin transporter in Alzheimer s and Parkinson s disease. - Immunopathogenic and clinical relevance of antibodies against myelin oligodendrocyte glycoprotein (MOG) in Multiple Sclerosis. - Lessons from studies of antigen-specific T cell responses in Multiple Sclerosis. - Glutamate excitotoxicity a mechanism for axonal damage and oligodendrocyte death in Multiple Sclerosis? . - Evidence for enhanced neuro-inflammatory processes in neurodegenerative diseases and the action of nitrones as potential therapeutics.
