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Inhaltsverzeichnis
I. Microcompartmentation and Energy Transport. - The Physiological Significance of the Creatine Phosphate Shuttle. - Organization of the Mitochondrial Matrix. - The Time Course of ATP Cleavage by Contracting Amphibian and Mammalian Skeletal Muscles. - Isozymes of Creatine Kinase in Mammalian Myocardial Cell Culture. - Microcompartmentation at the Mitochondrial Surface: Its Function in Metabolic Regulation. - The Effect of Inorganic Phosphate on Mitochondrial Creatine Kinase. - Hormonal Regulation of Creatine Kinase BB. - Compartmentation of Adenine Nucleotides and Phosphocreatine Shuttle in Cardiac Cells: Some New Evidence. - Compartmentation of Hormone Action in Adult Mammalian Cardiomyocytes. - Function of Creatine Kinase Localization in Muscle Contraction. - Isotope Labeling Ratios: A Tool for the Exploration of Metabolic Compartments. - The Mitochondrial Creatine Phosphokinase is Associated with Inner Membrane Cardiolipin. - A Role for Mitochondria in Myocardial Adenosine Production. - II. Respiration Control Cellular and Organ Level. - Aspects of Heart Respiratory Control by the Mitochondrial Isozyme of Creatine Kinase. - Control of Respiration in Intact Muscle. - Energy Compartmentation and Active Transport in Proximal Kidney Tubules. - The Oxygen Dependence of Cellular Energy Metabolism. - Regulation of Mitochondrial Respiration in Liver. - Quantitation of Fluxes in the Gluconeogenic, Glycolytic, and Pentose Phosphate Pathways in Isolated Rat Hepatocytes: Energetic Considerations. - Why is There a Delay in the Increased Oxygen Consumption During the Rest-Work Transition in Skeletal Muscles. - III. Myocardial Preservation, Ischemia: Cellular Mechanisms. - Compartmentation and Functional Mechanisms in Myocardial Failure and Myocardial Infarction. - Myocardial Protection ofHypertrophied Hearts by Administration of Cardioplegia According to Regional Myocardial Temperature. - Heart Myocytes as Models of the Cellular Response to Ischemia. - Biologic Basis for Limitation of Infarct Size. - Mitochondrial Transmembrane Proton Electrochemical Potential, Di- and Tricarboxylate Distribution and the Poise of the Malate-Aspartate Cycle in the Intact Myocardium. - Sarcomere Length-tension Relationship in Toad Atrioventricular Pacemaker: Length Dependent Activation. - Myocardial Acidosis and the Mitigation of Tissue ATP Depletion in Ischemic Cardiac Muscle: The Role of the Mitochondrial ATPase. - Vascular Metabolism and Energetics. - Myocardial Glutamate Dehydrogenase Activity. - Long Term Model for Evaluation of Myocardial Metabolic Recovery Following Global Ischemia. - The Effect of Reperfusion and Streptokinase on Ischemic Myocardium Serum Creatine Kinase Activity, MM Subtypes and Myocardial Blood Flow. - Post-contracture Reperfusion: Effect of Elevated Potassium and Verapamil. - Ultrastructure of the Human Myocardium after Intermittent Ischemia Compared to Cardioplegia. - IV. Pathophysiology of Energy Compartmentation. - Cellular Injury in Phosphate Depletion: Pathogenesis and Mechanisms in the Myocardium. - Diabetes Mellitus and Hypothyroidism Induce Changes in Myosin Isoenzyme Distribution in the Rat Heart Do Alterations in Fuel Flux Mediate These Changes? . - Glycerol Kinase Deficiency: Compartmental Considerations Regarding Pathogenesis and Clinical Heterogeneity. - Phosphorylated Nucleotides and Glycolytic Intermediates in Diabetic and Non-diabetic Rat uterus in Late Pregnancy. - Effect of Calcium Antagonists on Vasopressin Induced Changes in Myocardial and Renal Pyridine Nucleotides in the Intact Rat. - The Effect of Creatine Analogue Substitution on thePost Tetanic Response of Fast Muscle. - V. Divalent Ions and Cellular Bioenergetics. - Calcium Compartmentation in Mammalian Myocardium. - Calcium Channel Blockers, Beta Blockers and the Maintenance of Calcium Homeostasis. - Sodium-Calcium Exchange: Calcium Regulation at the Sarcolemma. - The Calcium Pumping ATPase of Heart Plasma Membrane. - Calcium Compartmentation and Regulation in Myocytes. - Ca++-Dependent and Ca++-Independent Effects of Mg++ on Canine Right Atria. - Chronotropic and Inotropic Effects of [Mg++]o Not Dependent upon [Ca++]o. - Sodium Modulation of Resting Force, Contractile Properties, and Metabolism with Particular Emphasis on its Role in the Development of Calcium Overload States. - The Effect of Short Chain Fatty Acid Administration on Hepatic Glucose, Phosphate, Magnesium and Calcium Metabolism. - VI. 31-P NMR. - Lessons for Muscle Energetics from 31P NMR Spectroscopy. - Metabolic Depletion Preceding Cytolysis Induced by Antibody and Complement as Revealed by 31P-NMR Spectroscopy.