Neurotransmitter Transporters

The volume aims at providing an overview of cutting-edge methods and protocols used in neuroscience and neurological research. Neurotransmitter Transporters: Investigative Methods will be of interest to scientists, graduate students, and advanced undergraduates who seek an overview of methods and protocols in this field of neuroscience. It will also be of interest to physicians who are carrying out imaging and postmortem studies of neurotransmitter transporters in the human brain. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.

Authoritative and practical, Neurotransmitter Transporters: Investigative Methods aims to ensure successful results in the
further study of this vital field.

Classical Radioligand Uptake and Binding Methods in Transporter Research: AnEmphasis on the Monoamine Neurotransmitter Transporters. - TracerFlux Measurements to Study Outward Transport by Monoamine Neurotransmitter Transporters. - Interrogatingthe Activity of Ligands at Monoamine Transporters in Rat Brain Synaptosomes. -- UsingHigh-Speed Chronoamperometry to Measure Biogenic Amine Release and Uptake InVivo. - ExperimentalData Guided Docking of Small Molecules Into Homology Models Of NeurotransmitterTransporters. - ImmunohistochemicalMethods for the Study of the Expression of Low-Affinity Monoamine Transportersin the Brain. - Analysisof Neurotransmitter Transporter Posttranslational Modifications: Phosphorylationand Palmitoylation. - Ensembleand Single Quantum Dot Fluorescence Methods in Neurotransmitter TransporterResearch. - Approachesfor Investigating Transporter Endocytic Trafficking In Cell Lines and NativePreparations. - Organic Cation Transport Measurements Using FluorescenceTechniques. - Animal Models for Depression and the Mode of Action ofNeurotransmitter Transporter-Blocking Antidepressants. - In-Vivo Imaging of Dopamine Metabolism and DopamineTransporter Function in the Human Brain.