The history of quinolones.- Structure-activity relationships of quinolones.- Epidemiology and mechanisms of resistance.- Improved safety profile of newer fluoroquinolones.- Pharmacokinetics and pharmacodynamics (PK/PD) of fluoro-quinolones: tools for combating bacteria and preventing resistance.- Fluoroquinolones in urinary tract infection.- The quinolones and sexually transmitted infections.- Gastrointestinal and intraabdominal infections.- The quinolones in otitis media and upper respiratory infections.- Quinolones in pneumonia.- Fluoroquinolones for the treatment of respiratory tractinfections other than pneumonia.- Quinolones for the treatment of skin, soft tissue, bone andprosthetic joint infections.- The role of fluoroquinolones in the therapy and prophylaxisof neutropenic patients with cancer.- Less usual indications: Mycobacterial, Brucella, Yersinia,Francisella and other infections.- The quinolones: future prospects.
Inhaltsverzeichnis
The history of quinolones. - Structure-activity relationships of quinolones. - Epidemiology and mechanisms of resistance. - Improved safety profile of newer fluoroquinolones. - Pharmacokinetics and pharmacodynamics (PK/PD) of fluoro-quinolones: tools for combating bacteria and preventing resistance. - Fluoroquinolones in urinary tract infection. - The quinolones and sexually transmitted infections. - Gastrointestinal and intraabdominal infections. - The quinolones in otitis media and upper respiratory infections. - Quinolones in pneumonia. - Fluoroquinolones for the treatment of respiratory tractinfections other than pneumonia. - Quinolones for the treatment of skin, soft tissue, bone andprosthetic joint infections. - The role of fluoroquinolones in the therapy and prophylaxisof neutropenic patients with cancer. - Less usual indications: Mycobacterial, Brucella, Yersinia, Francisella and other infections. - The quinolones: future prospects.
