Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.
Inhaltsverzeichnis
Part 1: Mechanisms of Brain Aging
1. Introduction to the Neurobiology of Aging
2. Neuronal Loss and Synaptic Dysfunction
3. Protein Misfolding and Aggregation and its role in dementia with Lewy bodies
4. Oxidative Stress and Aging
5. Inflammation: Chronic Inflammation in Aging
Part 2: Factors Influencing Brain Aging
6. Mitochondrial Dysfunction and Aging
7. Neurotransmitter Systems in Aging
8. Genetic Influences on Aging and Neurodegenerative Diseases
9. Environmental and Lifestyle Factors in Brain Aging
10. The Role of Diet in Brain Health
Part 3: Interventions and Strategies for Healthy Brain Aging
11. Exercise and Cognitive Function in Aging
12. Unlocking Cognitive Vitality: The Interplay of Stimulation, Sleep, and Brain Aging
13. Exploring the Multifaceted Links Between Comorbidities and Cognitive Aging
14. Therapeutic Approaches to Age-Related Cognitive Decline and Neurodegenerative Diseases
15. Exploring Promising Pharmaceutical Candidates for Anti-Aging
