In the era of precision medicine, the demand for smart and targeted drug delivery technologies is greater than ever. Redox-responsive delivery systems represent a cutting-edge approach that exploits the unique oxidative and reductive environments of diseased tissues to achieve site-specific therapeutic action.
This comprehensive volume brings together foundational knowledge, recent innovations, and application-specific insights into redox-sensitive systems used for drug, gene and vaccine delivery. The book covers a wide range of carriers-including polymersomes, liposomes, nanoparticles, micelles, prodrugs and dendrimers-highlighting their utility across various therapeutic landscapes, including cancer, neurodegenerative diseases, metabolic disorders, infectious diseases and gene editing platforms like CRISPR-Cas9.
Key Features:
- Explores the principles and design of redox-responsive materials
- Covers disease-specific applications, including Alzheimer's, Parkinson's, diabetes and antimicrobial resistance
- Discusses innovative delivery systems for siRNA and genome editing
- Addresses industrial translation, scale-up and commercialization challenges
- Authored by leading experts in pharmaceutics, nanomedicine and biomedical engineering
Ideal for pharmaceutical scientists, nanotechnologists, biomedical researchers and healthcare innovators, this book serves as a definitive guide to one of the most promising frontiers in drug delivery science.
Harness redox biology to revolutionize how therapeutics are delivered-safely, smartly and effectively.
Inhaltsverzeichnis
1. Introduction to Redox-Responsive Delivery Systems: Concepts and Significance 2. Redox-Responsive Delivery System for Cancer Treatment 3. Advancements and Challenges in Nucleic Acid Delivery through Redox Controlled Release Systems 4. Redox-Responsive Delivery System for Parkinson's Disease 5. Redox-Responsive Delivery System for Alzheimer's Disease 6. Redox-Responsive Based Polymersomes 7. Smart Redox-Responsive Nanocarriers: Revolutionizing Drug Delivery in Oxidative Diseases 8. Redox-Responsive-Based Nano Micelles 9. Redox-Responsive Based Liposomes 10. Redox-Responsive Delivery System for Prodrugs 11. Redox-Responsive Delivery Systems for Antimicrobial Resistance (AMR) Management 12. Redox-Responsive Based Nanoparticles 13. Redox-Responsive Based Nanoshell 14. Industrial Scale-up and Commercialization Challenges of Redox-Responsive Drug Delivery Systems 15. Redox-Responsive Drug Delivery in Dendrimers 16. Redox-Responsive Drug Delivery for Small Interfering RNA (siRNA) Delivery 17. Redox-Responsive Drug Delivery System for Diabetes Management 18. Redox-Responsive Systems in Gene Editing and CRISPR-Cas9 Delivery
