Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure.
Inhaltsverzeichnis
Inflammation a new frontier in cardiac disease and therapeutics. - Pathological aspects and inflammation biomarkers in cardiac diseases. - A biomarker of inflammation in cardiovascular diseases. - Inflammation and coronary artery disease. - Inflammatory cells and their metalloproteinases in cardiac diseases. - The role of matrix metalloproteinases in LV remodeling following myocardial infarction. - Matrix metalloproteinases in heart failure: evidence from experimental models. - Inflammatory cytokines in cardiac diseases. - The clinical experience with anti-cytokine therapy in heart failure. - The role of IL-6 and related cytokines in myocardial remodeling and inflammation implication for cardiac hypertrophy and heart failure. - Toll-like receptors and the cardiovascular system. - The role of IL-6 in experimental and clinical heart failure. - Oxygen and nitrogen reactive radicals in cardiac inflammation and disease. - Myocardial nitric oxide in cardiac remodeling. - Identification and role of inflammatory oxygen free radicals in cardiac ischemia and reperfusion injury. - The immune and complement system and cardiac diseases. - Immune-mediated myocarditis and interleukin-10. - Immunomodulation in heart failure: experimental models. - The role of complement in myocardial inflammation and reperfusion injury. - Inflammatory signaling pathways in cardiac diseases. - The role of immune and inflammatory cytokines in ischemic preconditioning of the heart identification of novel cardiac cell survival signaling programs. - Stress-activated signals and their role in myocardial ischemia. - p38 MAPK in cardiac remodeling and failure: cytokine signaling and beyond. - Inflammation and myocarditis. - Inflammation and myocarditis. - The inflammatory process in experimental myocarditis. - Nuclearfactors in cardiac disease. - Peroxisome proliferator activated receptors, inflammation, the vasculature and the heart. - Chemokines and cardiac diseases. - Role of chemokines in the pathogenesis of congestive heart failure. - Neurohormonal mediators and cardiac inflammation. - The role of endothelin-1 in myocardial inflammation and fibrosis. - Cyclooxygenases and cardiac diseases. - Cyclo-oxygenase-2 and myocardial ischemia. - Inflammation and arrhythmias. - Inflammation as a cause and consequence of atrial fibrillation. - Summary: Immune and inflammatory modulators as potential therapeutic targets for cardiac diseases.
