endoCANNABINOIDS

This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease.

Overview of Non-Cannabinoid Receptors. Overview of Non-Classical Cannabinoid Receptors. Overview of Non-Cannabinoid Receptors: Chemistry and Modeling. - G-Protein Coupled Receptors. GPR55 in the CNS. The Role of GPR55 in Bone Biology. The Role of GPR55 in Cancer. GPR18 and NAGly signaling: New members of the endocannabinoid family or distant cousins? . Cannabinoid Signaling Through Non CB1/Non CB2 GPCR Targets in Microglia. - Ion Channels. Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors. Nonpsychoactive Cannabinoid Action on 5-HT3 and Glycine Receptors. - Transcription Factors. Peroxisome proliferator-activated receptors and inflammation. Peroxisome proliferator-activated nuclear receptors (PPAR) and drug addiction. - Conclusions/Therapeutic Potential. Conclusions: Therapeutic Potential of Novel Cannabinoid Receptors.