Platelet-Rich Fibrin (PRF) and Platelet-Rich Plasma (PRP) have emerged as revolutionary tools in the field of periodontology, offering innovative and effective approaches for the treatment of various periodontal conditions. These autologous blood derivatives harness the regenerative potential of platelets, growth factors, and fibrin, promoting tissue healing and regeneration. The role of PRF and PRP in periodontology extends across surgical and non-surgical interventions, contributing to enhanced outcomes in periodontal therapy. In surgical procedures, PRF and PRP play a pivotal role in promoting tissue regeneration and wound healing. The process involves the collection of the patient's blood, which is then centrifuged to separate the various blood components. PRF is derived from this process and is characterized by a dense fibrin matrix, encapsulating a high concentration of platelets, leukocytes, and growth factors. When applied to surgical sites, PRF acts as a natural scaffold, facilitating cell migration and proliferation. This aids in the formation of new blood vessels (angiogenesis) and promotes the regeneration of periodontal tissues.
