Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.
Inhaltsverzeichnis
Pathophysiology and Diagnosis. - Unraveling the Complex Process of Restenosis From Bench to Bedside. - Epidemiology and Pathogenesis of Restenosis. - Clinical Presentation of Restenosis. - Pathological Anatomy of Restenosis. - The Influence of Shear Stress on Restenosis. - The Immune System in the Pathogenesis of Vascular Proliferative Disease. - Animal Restenosis Models. - Genetic Basis of Restenosis. - The Genomics of Restenosis. - Gene-Expression Profiling and Restenosis. - Proteomics and Restenosis. - Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation. - Cell Cycle Regulators and Vascular Proliferative Diseases. - Arterial Remodeling. - The Role of eNOS in Vascular Diseases. - Diagnosis of Restenosis. - The Use of Pressure Gradient in the Diagnosis of Restenosis. - The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease. - Magnetic Resonance Imaging for Restenosis. - Coronary Imaging With Multislice Spiral Computed Tomography. - Therapy of Restenosis. - Pharmacotherapy of Restenosis. - Brachytherapy. - Preclinical Data of Eluting Stents. - Clinical Data of Eluting Stents. - Biodegradable Stents. - Biotechnology in the Treatment of Restenosis. - Vascular Gene Therapy. - Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease. - Cell Cycle Approaches to the Treatment of In-Stent Restenosis. - Local Gene and Cell Delivery Devices.
