This book covers the basic principles and the clinical applications of nuclear oncology imaging techniques. It is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management. Nuclear Oncology: Pathophysiology and Clinical Applications is a comprehensive textbook covering the increasing role of radionuclide-based technologies in the management of oncologic patients, with disease-oriented chapters giving a detailed overview of current indications and developments. Topics covered include instrumentation, physics, radiobiology, radioguided surgery, and radionuclide therapy, which is discussed with useful separate topics describing the importance of organ function assessment after cancer therapies in the heart, lung, kidney and the gastro-intestinal tract. Additionally, significant aspects of cancer biology and molecular imaging are discussed, as well as appropriate tracers for both single- and positron-emitting radionuclides. Individual chapters in the book focus on the most common cancers occurring in adults and children, detailing radionuclide procedures within an integrated framework identifying the information required for effective treatment of specific tumors. These clinical chapters provide a description of the epidemiology, etiology, histologic and pathophysiologic classification, prognosis, treatment, and most common outcome for each type of cancer.
With contributions from a group of internationally-distinguished practitioners, Nuclear Oncology: Pathophysiology and Clinical Applications serves as a valuable compendium of knowledge for nuclear medicine physicians and radiologists and other clinicians involved in the care and management of cancer patients.
Inhaltsverzeichnis
I. Basic Science
1. The Cancer Biology of Molecular Imaging
2. Radiopharmaceuticals for Single-Photon Emission Imaging and for Therapy
3. Radiopharmaceuticals for Imaging in Oncology with Special Emphasis on Positron-Emitting Agents
4. Physics of Nuclear Oncology
5. Instrumentation
6. Radiobiology and Radiation Dosimetry in Nuclear Medicine: Therapy, Diagnosis, and Considerations for Sensitive Populations
II. Clinical Applications
7. Lymphomas
8. Multiple Myeloma
9. Brain Tumors
10. Head and Neck Cancer
11. Thyroid and Parathyroid Tumors
12. Breast Cancer
13. Lung and Mediastinal Tumors
14. Gastric Cancers
15. Cancers of the Esophagus and Small Bowel, Precancerous States of the Large Bowel, and Gastrointestinal Stromal Tumors
16. Tumors of the Liver and Biliary Tract
17. Pancreatic Cancer
18. Neuroendocrine Tumors
19. Colorectal Cancer
20. Kidney and Bladder Cancer
21. Tumors of the Genitourinary System
22. Gynecologic Cancers
23. Sarcoma
24. Malignant Melanoma
25. Pediatric Cancers
III. Radionuclide Therapy
26. I-131 MIBG Therapy
27. Targeted Therapy for Bone Metastasis
IV. Radioguided Surgery
28. Radioguided Surgery
V. Heart Disease in the Cancer Patient
29. Imaging the Heart in the Cancer Patient
VI. Adverse Effects of Cancer Therapy
30. Nuclear Medicine in the Assessment of Adverse Effects of Cancer Therapy in the Lung, Kidney, and Gastrointestinal Tract
VII. Teaching Cases
31. Cases
