Cellular Senescence

Detecting Cellular Senescence in Reprogramming. - DNA Damage In situ Ligation followed by Proximity Ligation Assay (DI-PLA). - Reactive Oxygen Species Detection in Senescent Cells. - Cellular Identification and Quantification of Senescence-associated ß-Galactosidase Activity in vivo. - Relative Human Telomere Length Quantification by Real-time PCR. - Assessing Functional Roles of the Senescence-associated Secretory Phenotype (SASP). - Measuring the Inflammasome in Oncogene-induced Senescence. - Alarmin Detection in Senescent Cells. - IMR90 ER:RAS: A Cell Model of Oncogene-induced Senescence. - Genotoxic Stress-induced Senescence. - A Multi-parametric Assay to Evaluate Senescent Cells. - A Novel Quantitative Method for the Detection of Lipofuscin, the Main Byproduct of Cellular Senescence, in Fluids. - Measurement of Metabolite Changes in Senescent Cells by Mass Spectrometry. - Quantification of Autophagy during Senescence. - Quantification of Aneuploidy in Mammalian Systems. - Identification of Genomic Alterations Through Multi-Level DNA Structural Analysis. - Mouse Models of Accelerated Cellular Senescence. - Methods to Quantify the NF-kB Pathway during Senescence.